Human GCSH/GCE/ NKH ORF/cDNA clone-Lentivirus plasmid (NM_004483)
Pre-made Human GCSH/GCE/ NKH Lentiviral expression plasmid for GCSH lentivirus packaging, GCSH lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMLP002763 | Human GCSH Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMLP002763 |
Gene Name | GCSH |
Accession Number | NM_004483 |
Gene ID | 2653 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 522 bp |
Gene Alias | GCE, NKH |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Sequence | ATGGCGCTGCGAGTGGTGCGGAGCGTGCGGGCCCTGCTCTGCACCCTGCGCGCGGTCCCGTCACCCGCCGCGCCCTGCCCGCCGAGGCCCTGGCAGCTGGGGGTGGGCGCCGTCCGTACGCTGCGCACTGGACCCGCTCTGCTCTCGGTGCGTAAATTCACAGAGAAACACGAATGGGTAACAACAGAAAATGGCATTGGAACAGTGGGAATCAGCAATTTTGCACAGGAAGCGTTGGGAGATGTTGTTTATTGTAGTCTCCCTGAAGTTGGGACAAAATTGAACAAACAAGATGAGTTTGGTGCTTTGGAAAGTGTGAAAGCTGCTAGTGAACTCTATTCTCCTTTATCAGGAGAAGTAACTGAAATTAATGAAGCTCTTGCAGAAAATCCAGGACTTGTAAACAAATCTTGTTATGAAGATGGTTGGCTGATCAAGATGACACTGAGTAACCCTTCAGAACTAGATGAACTTATGAGTGAAGAAGCATATGAGAAATACATAAAATCTATTGAGGAGTGA |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-SE1517-Ab | Anti-GCSH/ GCE/ NKH functional antibody |
Target Antigen | GM-Tg-g-SE1517-Ag | GCSH protein |
ORF Viral Vector | pGMLP002763 | Human GCSH Lentivirus plasmid |
ORF Viral Vector | pGMLP004014 | Human GCSH Lentivirus plasmid |
ORF Viral Vector | vGMLP002763 | Human GCSH Lentivirus particle |
ORF Viral Vector | vGMLP004014 | Human GCSH Lentivirus particle |
Target information
Target ID | GM-SE1517 |
Target Name | GCSH |
Gene ID | 2653, 68133, 717440, 171133, 101084333, 479633, 317723, 100629755 |
Gene Symbol and Synonyms | 1100001L02Rik,5730591C18Rik,GCE,GCSH,NKH |
Uniprot Accession | P23434 |
Uniprot Entry Name | GCSH_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Not Available |
Disease | Not Available |
Gene Ensembl | ENSG00000140905 |
Target Classification | Not Available |
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010]
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