Human MANF/ARMET/ ARP ORF/cDNA clone-Lentivirus plasmid (NM_006010)
Pre-made Human MANF/ARMET/ ARP Lentiviral expression plasmid for MANF lentivirus packaging, MANF lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMLP003144 | Human MANF Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMLP003144 |
Gene Name | MANF |
Accession Number | NM_006010 |
Gene ID | 7873 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 558 bp |
Gene Alias | ARMET, ARP |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Sequence | ATGAGGAGGATGAGGAGGATGTGGGCCACGCAGGGGCTGGCGGTGGCGCTGGCTCTGAGCGTGCTGCCGGGCAGCCGGGCGCTGCGGCCGGGCGACTGCGAAGTTTGTATTTCTTATCTGGGAAGATTTTACCAGGACCTCAAAGACAGAGATGTCACATTCTCACCAGCCACTATTGAAAACGAACTTATAAAGTTCTGCCGGGAAGCAAGAGGCAAAGAGAATCGGTTGTGCTACTATATCGGGGCCACAGATGATGCAGCCACCAAAATCATCAATGAGGTATCAAAGCCTCTGGCCCACCACATCCCTGTGGAGAAGATCTGTGAGAAGCTTAAGAAGAAGGACAGCCAGATATGTGAGCTTAAGTATGACAAGCAGATCGACCTGAGCACAGTGGACCTGAAGAAGCTCCGAGTTAAAGAGCTGAAGAAGATTCTGGATGACTGGGGGGAGACATGCAAAGGCTGTGCAGAAAAGTCTGACTACATCCGGAAGATAAATGAACTGATGCCTAAATATGCCCCCAAGGCAGCCAGTGCACGGACCGATTTGTAG |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T62415-Ab | Anti-MANF/ ARMET/ ARP functional antibody |
Target Antigen | GM-Tg-g-T62415-Ag | ARMET/MANF protein |
ORF Viral Vector | pGMLV000199 | Human MANF Lentivirus plasmid |
ORF Viral Vector | pGMLV000783 | Human MANF Lentivirus plasmid |
ORF Viral Vector | pGMLP003144 | Human MANF Lentivirus plasmid |
ORF Viral Vector | vGMLV000199 | Human MANF Lentivirus particle |
ORF Viral Vector | vGMLV000783 | Human MANF Lentivirus particle |
ORF Viral Vector | vGMLP003144 | Human MANF Lentivirus particle |
Target information
Target ID | GM-T62415 |
Target Name | ARMET |
Gene ID | 7873, 74840, 700659, 315989, 101090926, 100855747, 540432, 100052301 |
Gene Symbol and Synonyms | 3230402M22Rik,ARMET,ARP,D18Mgi17,MANF |
Uniprot Accession | P55145 |
Uniprot Entry Name | MANF_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | Not Available |
Gene Ensembl | ENSG00000145050 |
Target Classification | Not Available |
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014]
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