Human SLC22A18/BWR1A/BWSCR1A ORF/cDNA clone-Lentivirus plasmid (NM_002555)

Cat. No.: pGMLP003680
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SLC22A18/BWR1A/BWSCR1A Lentiviral expression plasmid for SLC22A18 lentivirus packaging, SLC22A18 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP003680
Gene Name SLC22A18
Accession Number NM_002555
Gene ID 5002
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1275 bp
Gene Alias BWR1A,BWSCR1A,HET,IMPT1,ITM,ORCTL2,p45-BWR1A,SLC22A1L,TSSC5
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCAGGGAGCTCGGGCTCCCAGGGACCAGGGCCGGTCCCCCGGCAGGATGAGCGCTCTAGGCCGGTCCTCGGTCATCTTGCTTACCTACGTGCTGGCCGCCACAGAACTTACCTGCCTCTTCATGCAGTTCTCCATCGTGCCATACCTGTCTCGGAAACTGGGCCTGGATTCCATTGCCTTCGGCTACCTGCAAACCACCTTCGGGGTGCTGCAGCTGCTGGGCGGGCCGGTATTTGGCAGGTTCGCAGACCAGCGCGGGGCGCGGGCGGCGCTCACGCTCTCCTTCCTGGCTGCCTTGGCGCTCTACCTGCTCCTGGCGGCCGCCTCCAGCCCGGCCCTGCCCGGGGTCTACCTGCTCTTCGCCTCGCGCCTGCCCGGAGCGCTCATGCACACGCTGCCAGCCGCCCAGATGGTCATCACGGACCTGTCGGCACCCGAGGAGCGGCCCGCGGCCCTGGGCCGGCTGGGCCTCTGCTTCGGCGTCGGAGTCATCCTCGGCTCCCTGCTGGGCGGGACCCTGGTCTCCGCGTACGGGATTCAGTGCCCGGCCATCCTGGCTGCCCTGGCCACCCTCCTGGGAGCTGTCCTCAGCTTCACCTGCATCCCCGCCAGCACCAAAGGGGCCAAAACTGACGCCCAGGCTCCACTGCCAGGCGGCCCCCGGGCCAGTGTGTTCGACCTGAAGGCCATCGCCTCCCTGCTGCGGCTGCCAGACGTCCCGAGGATCTTCCTGGTGAAGGTGGCCTCCAACTGCCCCACAGGGCTCTTCATGGTCATGTTCTCCATCATCTCCATGGACTTCTTCCAGCTGGAGGCCGCCCAAGCTGGCTACCTCATGTCCTTCTTCGGGCTCCTCCAGATGGTGACCCAGGGCCTGGTCATCGGGCAGCTGAGCAGCCACTTCTCGGAGGAGGTGCTGCTCCGGGCCAGCGTGCTGGTCTTCATCGTGGTGGGCCTGGCCATGGCCTGGATGTCCAGCGTCTTCCACTTCTGCCTCCTGGTGCCCGGCCTGGTGTTCAGCCTCTGCACCCTCAACGTGGTCACCGACAGCATGCTGATCAAGGCTGTCTCCACCTCGGACACAGGGACCATGCTGGGCCTCTGCGCCTCTGTACAACCACTGCTCCGAACTCTGGGACCCACGGTCGGCGGCCTCCTGTACCGCAGCTTTGGCGTCCCCGTCTTCGGCCACGTGCAGGTTGCTATCAATACCCTTGTCCTCCTGGTCCTCTGGAGGAAACCTATGCCCCAGAGGAAGGACAAAGTCCGGTGA
ORF Protein Sequence MQGARAPRDQGRSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP1560-Ab Anti-S22AI/ SLC22A18/ BWR1A monoclonal antibody
    Target Antigen GM-Tg-g-MP1560-Ag SLC22A18 VLP (virus-like particle)
    ORF Viral Vector pGMLP003680 Human SLC22A18 Lentivirus plasmid
    ORF Viral Vector vGMLP003680 Human SLC22A18 Lentivirus particle


    Target information

    Target ID GM-MP1560
    Target Name SLC22A18
    Gene ID 5002, 18400, 721230, 309131, 101092398, 475997, 504885, 100060198
    Gene Symbol and Synonyms BWR1A,BWSCR1A,HET,IMPT1,ITM,ORCTL2,p45-BWR1A,SLC22A18,SLC22A1L,TSSC5
    Uniprot Accession Q96BI1
    Uniprot Entry Name S22AI_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000110628
    Target Classification Tumor-associated antigen (TAA)

    This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2015]



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