Human LZTS2/LAPSER1 ORF/cDNA clone-Lentivirus plasmid (NM_001318100)

Cat. No.: pGMLP003811
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human LZTS2/LAPSER1 Lentiviral expression plasmid for LZTS2 lentivirus packaging, LZTS2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP003811
Gene Name LZTS2
Accession Number NM_001318100
Gene ID 84445
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2010 bp
Gene Alias LAPSER1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCCATTGTGCAGACTCTGCCAGTGCCACTGGAGCCTGCTCCTGAAGCTGCCACTGCCCCACAAGCTCCAGTCATGGGTAGTGTGAGCAGCCTTATCTCAGGCCGGCCCTGTCCCGGGGGGCCAGCTCCTCCCCGCCACCACGGCCCTCCTGGGCCCACCTTCTTCCGCCAGCAGGATGGCCTGCTACGGGGTGGCTATGAGGCACAGGAGCCGCTGTGCCCAGCTGTGCCCCCTAGGAAGGCTGTCCCTGTCACCAGCTTCACCTACATCAATGAGGACTTCCGGACAGAGTCACCCCCCAGCCCAAGCAGTGATGTTGAGGATGCCCGAGAGCAGCGGGCACACAATGCCCACCTCCGCGGCCCACCACCAAAGCTCATCCCTGTCTCTGGAAAGCTGGAGAAGAACATGGAGAAGATCCTGATCCGCCCAACAGCCTTCAAGCCAGTGCTGCCCAAACCTCGAGGGGCTCCGTCCCTGCCTAGCTTCATGGGTCCTCGGGCCACCGGGCTGTCTGGGAGCCAGGGCAGCCTGACGCAGCTGTTTGGGGGCCCTGCCTCCTCCTCCTCCTCTTCCTCCTCCTCTTCAGCTGCTGACAAACCCCTGGCATTTAGTGGCTGGGCCAGTGGCTGCCCATCAGGGACGCTATCCGACTCTGGCCGAAACTCACTGTCCAGCCTGCCCACCTACAGCACCGGAGGTGCCGAGCCAACCACCAGCTCCCCAGGCGGGCACCTGCCTTCCCATGGCTCTGGGCGAGGGGCACTGCCTGGGCCAGCCCGAGGGGTCCCTACTGGGCCCTCCCACTCAGACAGTGGCCGGTCCTCCTCCAGCAAGAGCACAGGCTCCCTAGGGGGCCGTGTGGCTGGGGGGCTTTTGGGCAGTGGTACTCGGGCCTCCCCTGACAGCAGCTCCTGTGGGGAGCGCTCACCACCACCCCCGCCTCCACCTCCTTCGGATGAGGCCCTGCTGCACTGTGTCCTGGAAGGAAAGCTCCGAGACCGGGAGGCAGAGCTTCAGCAGCTGCGGGACAGTCTGGACGAGAATGAGGCTACCATGTGCCAGGCATACGAGGAGCGGCAGCGGCACTGGCAGCGAGAGCGTGAGGCCCTGCGAGAGGACTGTGCGGCCCAGGCACAGCGGGCACAGCGGGCCCAACAGCTGCTGCAGCTGCAGGTGTTCCAGCTGCAGCAGGAGAAGCGGCAATTGCAGGACGACTTCGCACAGCTGCTGCAGGAGCGCGAACAGCTGGAGCGGCGCTGCGCCACCTTGGAGCGGGAGCAGCGGGAGCTCGGGCCGAGGCTTGAGGAGACCAAGTGGGAGGTGTGCCAGAAATCAGGCGAGATCTCCCTGCTGAAGCAGCAGCTGAAAGAGTCTCAGGCAGAGCTGGTGCAGAAGGGCAGCGAGCTGGTGGCTCTGCGGGTGGCGCTGCGGGAGGCCCGTGCTACGCTGCGGGTCAGTGAGGGCCGTGCGCGGGGTCTACAGGAGGCCGCCCGAGCTCGGGAGCTGGAGCTGGAAGCCTGTTCCCAGGAGCTGCAGCGACACCGCCAGGAAGCTGAGCAGCTGCGGGAGAAAGCTGGGCAGTTGGATGCTGAGGCGGCCGGACTCCGGGAGCCCCCTGTGCCACCTGCCACCGCTGACCCATTCCTCCTGGCAGAGAGTGATGAGGCCAAAGTGCAGCGGGCAGCAGCCGGGGTTGGGGGCAGCTTGCGGGCCCAGGTGGAGCGATTGCGGGTGGAGCTGCAGCGGGAGCGGCGGCGGGGTGAGGAGCAGCGGGACAGCTTTGAGGGGGAGCGGCTGGCCTGGCAGGCAGAGAAGGAGCAGGTGATCCGCTACCAGAAGCAGCTGCAGCACAACTACATCCAGATGTACCGGCGCAACCGGCAGCTAGAGCAGGAGCTGCAGCAGCTCAGCCTGGAGCTGGAGGCCCGGGAGCTCGCTGACCTGGGCCTGGCCGAGCAGGCCCCCTGCATCTGCCTGGAGGAGATCACTGCTACTGAGATCTAG
ORF Protein Sequence MAIVQTLPVPLEPAPEAATAPQAPVMGSVSSLISGRPCPGGPAPPRHHGPPGPTFFRQQDGLLRGGYEAQEPLCPAVPPRKAVPVTSFTYINEDFRTESPPSPSSDVEDAREQRAHNAHLRGPPPKLIPVSGKLEKNMEKILIRPTAFKPVLPKPRGAPSLPSFMGPRATGLSGSQGSLTQLFGGPASSSSSSSSSSAADKPLAFSGWASGCPSGTLSDSGRNSLSSLPTYSTGGAEPTTSSPGGHLPSHGSGRGALPGPARGVPTGPSHSDSGRSSSSKSTGSLGGRVAGGLLGSGTRASPDSSSCGERSPPPPPPPPSDEALLHCVLEGKLRDREAELQQLRDSLDENEATMCQAYEERQRHWQREREALREDCAAQAQRAQRAQQLLQLQVFQLQQEKRQLQDDFAQLLQEREQLERRCATLEREQRELGPRLEETKWEVCQKSGEISLLKQQLKESQAELVQKGSELVALRVALREARATLRVSEGRARGLQEAARARELELEACSQELQRHRQEAEQLREKAGQLDAEAAGLREPPVPPATADPFLLAESDEAKVQRAAAGVGGSLRAQVERLRVELQRERRRGEEQRDSFEGERLAWQAEKEQVIRYQKQLQHNYIQMYRRNRQLEQELQQLSLELEARELADLGLAEQAPCICLEEITATEI

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2190-Ab Anti-LZTS2/ LAPSER1 monoclonal antibody
    Target Antigen GM-Tg-g-MP2190-Ag LZTS2 VLP (virus-like particle)
    ORF Viral Vector pGMLP003811 Human LZTS2 Lentivirus plasmid
    ORF Viral Vector vGMLP003811 Human LZTS2 Lentivirus particle


    Target information

    Target ID GM-MP2190
    Target Name LZTS2
    Gene ID 84445, 226154, 711279, 365468, 101094378, 486846, 504411, 100060415
    Gene Symbol and Synonyms LAPSER1,LZTS2,mKIAA1813
    Uniprot Accession Q9BRK4
    Uniprot Entry Name LZTS2_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000107816
    Target Classification Not Available

    The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]



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