Human MMP7/MMP-7/ MPSL1 ORF/cDNA clone-Lentivirus plasmid (NM_002423)

Pre-made Human MMP7/MMP-7/ MPSL1 Lentiviral expression plasmid for MMP7 lentivirus packaging, MMP7 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collectionGo to MMP-7/MMP7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLP003953 Human MMP7 Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMLP003953
Gene Name MMP7
Accession Number NM_002423
Gene ID 4316
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 804 bp
Gene Alias MMP-7, MPSL1, PUMP-1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
Sequence ATGCGACTCACCGTGCTGTGTGCTGTGTGCCTGCTGCCTGGCAGCCTGGCCCTGCCGCTGCCTCAGGAGGCGGGAGGCATGAGTGAGCTACAGTGGGAACAGGCTCAGGACTATCTCAAGAGATTTTATCTCTATGACTCAGAAACAAAAAATGCCAACAGTTTAGAAGCCAAACTCAAGGAGATGCAAAAATTCTTTGGCCTACCTATAACTGGAATGTTAAACTCCCGCGTCATAGAAATAATGCAGAAGCCCAGATGTGGAGTGCCAGATGTTGCAGAATACTCACTATTTCCAAATAGCCCAAAATGGACTTCCAAAGTGGTCACCTACAGGATCGTATCATATACTCGAGACTTACCGCATATTACAGTGGATCGATTAGTGTCAAAGGCTTTAAACATGTGGGGCAAAGAGATCCCCCTGCATTTCAGGAAAGTTGTATGGGGAACTGCTGACATCATGATTGGCTTTGCGCGAGGAGCTCATGGGGACTCCTACCCATTTGATGGGCCAGGAAACACGCTGGCTCATGCCTTTGCGCCTGGGACAGGTCTCGGAGGAGATGCTCACTTCGATGAGGATGAACGCTGGACGGATGGTAGCAGTCTAGGGATTAACTTCCTGTATGCTGCAACTCATGAACTTGGCCATTCTTTGGGTATGGGACATTCCTCTGATCCTAATGCAGTGATGTATCCAACCTATGGAAATGGAGATCCCCAAAATTTTAAACTTTCCCAGGATGATATTAAAGGCATTCAGAAACTATATGGAAAGAGAAGTAATTCAAGAAAGAAATAG

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T73475-Ab Anti-MMP7/ MMP-7/ MPSL1 functional antibody
    Target Antigen GM-Tg-g-T73475-Ag MMP-7/MMP7 protein
    ORF Viral Vector pGMPC000761 Human MMP7 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMLP003953 Human MMP7 Lentivirus plasmid
    ORF Viral Vector vGMLP003953 Human MMP7 Lentivirus particle
    ORF Viral Vector pGMLV002265 Human MMP7 Lentivirus plasmid


    Target information

    Target ID GM-T73475
    Target Name MMP-7
    Gene ID 4316, 17393, 703072, 25335, 727698, 489432, 286794, 100068985
    Gene Symbol and Synonyms MAT,Matrilysin,MMP-7,MMP7,MPMM,MPSL1,PUMP-1
    Uniprot Accession P09237
    Uniprot Entry Name MMP7_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Ovary Cancer, Chronic Kidney Disease
    Gene Ensembl ENSG00000137673
    Target Classification Not Available

    This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]



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