Human EEF1E1/AIMP3/P18 ORF/cDNA clone-Lentivirus plasmid (NM_004280)

Cat. No.: pGMLP004631
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human EEF1E1/AIMP3/P18 Lentiviral expression plasmid for EEF1E1 lentivirus packaging, EEF1E1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP004631
Gene Name EEF1E1
Accession Number NM_004280
Gene ID 9521
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 525 bp
Gene Alias AIMP3,P18
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCGGCGGCCGCAGAGTTGTCGCTACTGGAGAAGTCCCTGGGACTGAGTAAGGGGAATAAATACAGTGCTCAGGGCGAGCGACAGATTCCAGTTCTTCAGACAAACAATGGTCCAAGTCTAACAGGATTGACTACTATAGCAGCTCATCTAGTCAAGCAAGCCAACAAAGAATATTTGCTGGGGAGTACTGCAGAAGAAAAAGCAATCGTTCAGCAGTGGTTAGAATACAGGGTCACTCAAGTAGATGGGCACTCCAGTAAAAATGACATCCACACACTGTTGAAGGATCTTAATTCATATCTTGAAGATAAAGTCTACCTTACAGGGTATAACTTTACATTAGCAGATATACTATTGTACTATGGACTTCATCGCTTTATAGTTGACCTGACAGTTCAAGAAAAGGAGAAATATCTTAATGTGTCTCGCTGGTTTTGTCACATTCAGCATTATCCAGGCATCAGGCAACATCTGTCTAGTGTTGTCTTCATCAAGAACAGACTATATACTAATTCCCACTAG
ORF Protein Sequence MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHYPGIRQHLSSVVFIKNRLYTNSH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0740-Ab Anti-EEF1E1 monoclonal antibody
    Target Antigen GM-Tg-g-IP0740-Ag EEF1E1 protein
    ORF Viral Vector pGMLP004631 Human EEF1E1 Lentivirus plasmid
    ORF Viral Vector vGMLP004631 Human EEF1E1 Lentivirus particle


    Target information

    Target ID GM-IP0740
    Target Name EEF1E1
    Gene ID 9521, 66143, 695426, 291057, 101097893, 478717, 617105, 100062116
    Gene Symbol and Synonyms 1110003A02Rik,AIMP3,EEF1E1,P18
    Uniprot Accession O43324
    Uniprot Entry Name MCA3_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000124802
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010]



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