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Anti-EEF1E1 monoclonal antibody
Pre-made anti-EEF1E1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to EEF1E1/EEF1E1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0740-Ab-1/ GM-Tg-hg-IP0740-Ab-2 | Anti-Human EEF1E1 monoclonal antibody | Human |
| GM-Tg-rg-IP0740-Ab-1/ GM-Tg-rg-IP0740-Ab-2 | Anti-Rat EEF1E1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0740-Ab-1/ GM-Tg-mg-IP0740-Ab-2 | Anti-Mouse EEF1E1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0740-Ab-1/ GM-Tg-cynog-IP0740-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EEF1E1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0740-Ab-1/ GM-Tg-felg-IP0740-Ab-2 | Anti-Feline EEF1E1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0740-Ab-1/ GM-Tg-cang-IP0740-Ab-2 | Anti-Canine EEF1E1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0740-Ab-1/ GM-Tg-bovg-IP0740-Ab-2 | Anti-Bovine EEF1E1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0740-Ab-1/ GM-Tg-equg-IP0740-Ab-2 | Anti-Equine EEF1E1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0740-Ab-1/ GM-Tg-hg-IP0740-Ab-2; GM-Tg-rg-IP0740-Ab-1/ GM-Tg-rg-IP0740-Ab-2; GM-Tg-mg-IP0740-Ab-1/ GM-Tg-mg-IP0740-Ab-2; GM-Tg-cynog-IP0740-Ab-1/ GM-Tg-cynog-IP0740-Ab-2; GM-Tg-felg-IP0740-Ab-1/ GM-Tg-felg-IP0740-Ab-2; GM-Tg-cang-IP0740-Ab-1/ GM-Tg-cang-IP0740-Ab-2; GM-Tg-bovg-IP0740-Ab-1/ GM-Tg-bovg-IP0740-Ab-2; GM-Tg-equg-IP0740-Ab-1/ GM-Tg-equg-IP0740-Ab-2 |
| Products Name | Anti-EEF1E1 monoclonal antibody |
| Format | mab |
| Target Name | EEF1E1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-EEF1E1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0740-Ag-1 | Recombinant multi-species MCA3/ EEF1E1/ AIMP3 protein |
| ORF Viral Vector | pGMLP004631 | human EEF1E1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004631 | human EEF1E1 Lentivirus particle |
| ORF Viral Vector | pGMLPm002387 | mouse Eef1e1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002387 | mouse Eef1e1 Lentivirus particle |
Target information
| Target ID | GM-IP0740 |
| Target Name | EEF1E1 |
| Gene ID | 9521,66143,291057,695426,478717,101097893,617105,100062116 |
| Gene Symbol and Synonyms | 1110003A02Rik,AIMP3,EEF1E1,P18 |
| Uniprot Accession | O43324 |
| Uniprot Entry Name | MCA3_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000124802 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: EEF1E1, gene name: EEF1E1, also named as AIMP3, P18. This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in A™/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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