Human HRAS/C-BAS/HAS/C-H-RAS ORF/cDNA clone-Lentivirus plasmid (NM_005343.3)

Cat. No.: pGMLP005795
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human HRAS/C-BAS/HAS/C-H-RAS Lentiviral expression plasmid for HRAS lentivirus packaging, HRAS lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP005795
Gene Name HRAS
Accession Number NM_005343.3
Gene ID 3265
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 570 bp
Gene Alias C-BAS/HAS,C-H-RAS,C-HA-RAS1,c-K-ras,c-Ki-ras,CTLO,H-RASIDX,HAMSV,HRAS1,Ki-Ras,KRAS,KRAS2,p21ras,RASH1,RASK2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGACGGAATATAAGCTGGTGGTGGTGGGCGCCGGCGGTGTGGGCAAGAGTGCGCTGACCATCCAGCTGATCCAGAACCATTTTGTGGACGAATACGACCCCACTATAGAGGATTCCTACCGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATCCTGGATACCGCCGGCCAGGAGGAGTACAGCGCCATGCGGGACCAGTACATGCGCACCGGGGAGGGCTTCCTGTGTGTGTTTGCCATCAACAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGGAGCAGATCAAACGGGTGAAGGACTCGGATGACGTGCCCATGGTGCTGGTGGGGAACAAGTGTGACCTGGCTGCACGCACTGTGGAATCTCGGCAGGCTCAGGACCTCGCCCGAAGCTACGGCATCCCCTACATCGAGACCTCGGCCAAGACCCGGCAGGGAGTGGAGGATGCCTTCTACACGTTGGTGCGTGAGATCCGGCAGCACAAGCTGCGGAAGCTGAACCCTCCTGATGAGAGTGGCCCCGGCTGCATGAGCTGCAAGTGTGTGCTCTCCTGA
ORF Protein Sequence MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T71081-Ab Anti-HRAS monoclonal antibody
    Target Antigen GM-Tg-g-T71081-Ag HRAS protein
    ORF Viral Vector pGMLP000856 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005584 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005791 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005792 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005793 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005794 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005795 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005796 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005797 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005798 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005799 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP005808 Human HRAS Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-052 Human HRas Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-192 Human HRas Adenovirus plasmid
    ORF Viral Vector vGMLP000856 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005584 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005791 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005792 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005793 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005794 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005795 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005796 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005797 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005798 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005799 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP005808 Human HRAS Lentivirus particle
    ORF Viral Vector vGMLP-SPh-052 Human HRas Lentivirus particle
    ORF Viral Vector vGMAP-SPh-192 Human HRas Adenovirus particle


    Target information

    Target ID GM-T71081
    Target Name HRAS
    Gene ID 3265, 15461, 698830, 293621, 751103, 403735, 100298939, 100055481
    Gene Symbol and Synonyms C-BAS/HAS,C-H-RAS,c-Ha-ras,C-HA-RAS1,c-rasHa,CTLO,H-ras,H-RASIDX,Ha-ras,HAMSV,Harvey-ras,HRAS,Hras-1,HRAS1,Kras2,p21ras,ras,RASH1
    Uniprot Accession P01112
    Uniprot Entry Name RASH_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Non-Small Cell Lung Cancer
    Gene Ensembl ENSG00000174775
    Target Classification Not Available

    This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]



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