Human ITCH/ADMFD/ AIF4 ORF/cDNA clone-Lentivirus plasmid (NM_031483.4)

Pre-made Human ITCH/ADMFD/ AIF4 Lentiviral expression plasmid for ITCH lentivirus packaging, ITCH lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

Target products collectionGo to ITCH/ADMFD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000051 Human ITCH Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug

Product Description

Catalog ID pGMLV000051
Gene Name ITCH
Accession Number NM_031483.4
Gene ID 83737
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2589 bp
Gene Alias ADMFD, AIF4, AIP4, NAPP1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag Null
Promoter CMV
Resistance Amplicin


    Data / case study

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    Associated products

    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T81240-Ab Anti-ITCH monoclonal antibody
    Target Antigen GM-Tg-g-T81240-Ag ITCH protein
    ORF Viral Vector pGMLV000051 Human ITCH Lentivirus plasmid
    ORF Viral Vector pGMPC001096 Human ITCH Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000051 Human ITCH Lentivirus particle

    Target information

    Target ID GM-T81240
    Target Name ITCH
    Gene ID 83737, 16396, 707640, 311567, 101086133, 477199, 508431, 100069340
    Gene Symbol and Synonyms 6720481N21Rik,8030492O04Rik,A130065M08,ADMFD,AIF4,AIP4,C230047C07Rik,ITCH,NAPP1
    Uniprot Accession Q96J02
    Uniprot Entry Name ITCH_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000078747
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

    About GMVC


    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.