Recombinant multi-species ITCH/ ADMFD/ AIF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ITCH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ITCH, gene name: ITCH, also named as ADMFD, AIF4, AIP4, NAPP1. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T81240-Ag-1	Human ITCH protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T81240-Ag-1	Rat ITCH protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T81240-Ag-1	Mouse ITCH protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T81240-Ag-1	Cynomolgus/ Rhesus macaque ITCH protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T81240-Ag-1	Feline ITCH protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T81240-Ag-1	Canine ITCH protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T81240-Ag-1	Bovine ITCH protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T81240-Ag-1	Equine ITCH protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T81240-Ag, GM-Tg-rg-T81240-Ag, GM-Tg-mg-T81240-Ag, GM-Tg-cynog-T81240-Ag, GM-Tg-felg-T81240-Ag, GM-Tg-cang-T81240-Ag, GM-Tg-bovg-T81240-Ag, GM-Tg-equg-T81240-Ag-1
Products Name	ITCH protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	ITCH
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ITCH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.