Human ABCB1/ABC20/ CD243 ORF/cDNA clone-Lentivirus plasmid (NM_000927.4)

Pre-made Human ABCB1/ABC20/ CD243 Lentiviral expression plasmid for ABCB1 lentivirus packaging, ABCB1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

Target products collectionGo to ABCB1/ABC20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000440 Human ABCB1 Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug

Product Description

Catalog ID pGMLV000440
Gene Name ABCB1
Accession Number NM_000927.4
Gene ID 5243
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 3843 bp
Gene Alias ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1, p-170
Fluorescent Reporter
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin


    Data / case study

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    Associated products

    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T25258-Ab Anti-MDR1/ ABCB1/ ABC20 monoclonal antibody
    Target Antigen GM-Tg-g-T25258-Ag ABCB1 VLP (virus-like particle)
    ORF Viral Vector pGMLV000440 Human ABCB1 Lentivirus plasmid
    ORF Viral Vector pGMPC000332 Human ABCB1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000440 Human ABCB1 Lentivirus particle

    Target information

    Target ID GM-T25258
    Target Name ABCB1
    Gene ID 5243, 18669, 574235, 493707, 403879, 100034074
    Gene Symbol and Synonyms ABC20,ABCB1,Abcb1b,CD243,CLCS,GP170,mdr,MDR1,Mdr1b,p-170,P-GP,Pgy-1,PGY1
    Uniprot Accession P08183
    Uniprot Entry Name MDR1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000085563
    Target Classification Tumor-associated antigen (TAA)

    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Feb 2017]

    About GMVC


    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.