Human FGFR4/CD334/ JTK2 ORF/cDNA clone-Lentivirus plasmid (NM_213647.2)

Pre-made Human FGFR4/CD334/ JTK2 Lentiviral expression plasmid for FGFR4 lentivirus packaging, FGFR4 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

Target products collectionGo to FGFR4/CD334 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000558 Human FGFR4 Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMLV000558
Gene Name FGFR4
Accession Number NM_213647.2
Gene ID 2264
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2409 bp
Gene Alias CD334, JTK2, TKF
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-INN-727 Pre-Made Aldafermin Biosimilar, Recombinant Protein targeting FGFR4: Recombinant therapeutic protein targeting CD334/JTK2/TKF
    Target Antibody GM-Tg-g-T90989-Ab Anti-FGFR4/ CD334/ JTK2 monoclonal antibody
    Target Antigen GM-Tg-g-T90989-Ag FGFR4 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T90989 Fibroblast growth factor receptor 4 (FGFR4) protein & antibody
    ORF Viral Vector pGMLV000558 Human FGFR4 Lentivirus plasmid
    ORF Viral Vector vGMLV000558 Human FGFR4 Lentivirus particle


    Target information

    Target ID GM-T90989
    Target Name FGFR4
    Gene ID 2264, 14186, 698494, 25114, 101100864, 489095, 317696, 100068679
    Gene Symbol and Synonyms CD334,Fgfr-4,FGFR4,JTK2,TKF
    Uniprot Accession P22455
    Uniprot Entry Name FGFR4_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, INN Index, Cytokine Target
    Disease Breast Cancer, Ovary Cancer
    Gene Ensembl ENSG00000160867
    Target Classification Kinase

    The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.