Human CD99/HBA71/MIC2 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_002414)

Cat. No.: pGMPC000443
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CD99/HBA71/MIC2 Non-Viral expression plasmid (overexpression vector) for mouse CD99 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000443
Gene Name CD99
Accession Number NM_002414
Gene ID 4267
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 558 bp
Gene Alias HBA71,MIC2,MIC2X,MIC2Y,MSK5X
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGGCCCGCGGGGCTGCGCTGGCGCTGCTGCTCTTCGGCCTGCTGGGTGTTCTGGTCGCCGCCCCGGATGGTGGTTTCGATTTATCCGATGCCCTTCCTGACAATGAAAACAAGAAACCCACTGCAATCCCCAAGAAACCCAGTGCTGGGGATGACTTTGACTTAGGAGATGCTGTTGTTGATGGAGAAAATGACGACCCACGACCACCGAACCCACCCAAACCGATGCCAAATCCAAACCCCAACCACCCTAGTTCCTCCGGTAGCTTTTCAGATGCTGACCTTGCGGATGGCGTTTCAGGTGGAGAAGGAAAAGGAGGCAGTGATGGTGGAGGCAGCCACAGGAAAGAAGGGGAAGAGGCCGACGCCCCAGGCGTGATCCCCGGGATTGTGGGGGCTGTCGTGGTCGCCGTGGCTGGAGCCATCTCTAGCTTCATTGCTTACCAGAAAAAGAAGCTATGCTTCAAAGAAAATGCAGAACAAGGGGAGGTGGACATGGAGAGCCACCGGAATGCCAACGCAGAGCCAGCTGTTCAGCGTACTCTTTTAGAGAAATAG
ORF Protein Sequence MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVVDGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQRTLLEK

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IO103-Ab Anti-CD99/ MIC2/ HBA71 monoclonal antibody
    Target Antigen GM-Tg-g-IO103-Ag MIC2/CD99 VLP (virus-like particle)
    ORF Viral Vector pGMLP004612 Human CD99 Lentivirus plasmid
    ORF Viral Vector pGMPC000443 Human CD99 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP004612 Human CD99 Lentivirus particle


    Target information

    Target ID GM-IO103
    Target Name MIC2
    Gene ID 4267, 720563, 102902569, 609832, 509230, 100064394
    Gene Symbol and Synonyms CD99,HBA71,MIC2,MIC2X,MIC2Y,MSK5X
    Uniprot Accession P14209
    Uniprot Entry Name CD99_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease Cancer
    Gene Ensembl ENSG00000002586
    Target Classification Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)

    The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016]



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