Human AURKB/AIK2/AIM-1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_004217.4)

Cat. No.: pGMPC000527
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human AURKB/AIK2/AIM-1 Non-Viral expression plasmid (overexpression vector) for mouse AURKB overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000527
Gene Name AURKB
Accession Number NM_004217.4
Gene ID 9212
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1035 bp
Gene Alias AIK2,AIM-1,AIM1,ARK-2,ARK2,AurB,aurkb-sv1,aurkb-sv2,IPL1,PPP1R48,STK-1,STK12,STK5
Fluorescent Reporter Null
Mammalian Cell Selection Puromyocin
Fusion Tag Null
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCCCAGAAGGAGAACTCCTACCCCTGGCCCTACGGCCGACAGACGGCTCCATCTGGCCTGAGCACCCTGCCCCAGCGAGTCCTCCGGAAAGAGCCTGTCACCCCATCTGCACTTGTCCTCATGAGCCGCTCCAATGTCCAGCCCACAGCTGCCCCTGGCCAGAAGGTGATGGAGAATAGCAGTGGGACACCCGACATCTTAACGCGGCACTTCACAATTGATGACTTTGAGATTGGGCGTCCTCTGGGCAAAGGCAAGTTTGGAAACGTGTACTTGGCTCGGGAGAAGAAAAGCCATTTCATCGTGGCGCTCAAGGTCCTCTTCAAGTCCCAGATAGAGAAGGAGGGCGTGGAGCATCAGCTGCGCAGAGAGATCGAAATCCAGGCCCACCTGCACCATCCCAACATCCTGCGTCTCTACAACTATTTTTATGACCGGAGGAGGATCTACTTGATTCTAGAGTATGCCCCCCGCGGGGAGCTCTACAAGGAGCTGCAGAAGAGCTGCACATTTGACGAGCAGCGAACAGCCACGATCATGGAGGAGTTGGCAGATGCTCTAATGTACTGCCATGGGAAGAAGGTGATTCACAGAGACATAAAGCCAGAAAATCTGCTCTTAGGGCTCAAGGGAGAGCTGAAGATTGCTGACTTCGGCTGGTCTGTGCATGCGCCCTCCCTGAGGAGGAAGACAATGTGTGGCACCCTGGACTACCTGCCCCCAGAGATGATTGAGGGGCGCATGCACAATGAGAAGGTGGATCTGTGGTGCATTGGAGTGCTTTGCTATGAGCTGCTGGTGGGGAACCCACCCTTTGAGAGTGCATCACACAACGAGACCTATCGCCGCATCGTCAAGGTGGACCTAAAGTTCCCCGCTTCCGTGCCCATGGGAGCCCAGGACCTCATCTCCAAACTGCTCAGGCATAACCCCTCGGAACGGCTGCCCCTGGCCCAGGTCTCAGCCCACCCTTGGGTCCGGGCCAACTCTCGGAGGGTGCTGCCTCCCTCTGCCCTTCAATCTGTCGCCTGA
ORF Protein Sequence MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T46781-Ab Anti-AURKB monoclonal antibody
    Target Antigen GM-Tg-g-T46781-Ag AURKB protein
    ORF Viral Vector pGMLP005299 Human AURKB Lentivirus plasmid
    ORF Viral Vector pGMPC000527 Human AURKB Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005299 Human AURKB Lentivirus particle


    Target information

    Target ID GM-T46781
    Target Name AURKB
    Gene ID 9212, 20877, 721955, 114592, 101081264, 479492, 360192, 100073050
    Gene Symbol and Synonyms AIK2,AIM-1,AIM1,AIRK2,ARK-2,ARK2,AurB,AURKB,aurkb-sv1,aurkb-sv2,IPL1,PPP1R48,STK-1,STK12,STK5
    Uniprot Accession Q96GD4
    Uniprot Entry Name AURKB_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000178999
    Target Classification Kinase, Tumor-associated antigen (TAA)

    This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]



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