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Human KLF4/EZF/ GKLF ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_001314052.2)
Pre-made Human KLF4/EZF/ GKLF Non-Viral expression plasmid (overexpression vector) for mouse KLF4 overexpression in unique cell transient transfection and stable cell line development.
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Product information
| Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
|---|---|---|---|
| pGMPC001122 | Human KLF4 Mammalian (Non-Viral Vector) plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
| GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
| High Quality (HQ) Grade | |||
| Seed | 5ug |
Product Description
| Catalog ID | pGMPC001122 |
| Gene Name | KLF4 |
| Accession Number | NM_001314052.2 |
| Gene ID | 9314 |
| Species | Human |
| Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
| Insert Length | 1542 bp |
| Gene Alias | EZF, GKLF |
| Fluorescent Reporter | Luciferase |
| Mammalian Cell Selection | |
| Fusion Tag | Null |
| Promoter | CMV |
| Resistance | Amplicin |
| Sequence | ATGAGGCAGCCACCTGGCGAGTCTGACATGGCTGTCAGCGACGCGCTGCTCCCATCTTTCTCCACGTTCGCGTCTGGCCCGGCGGGAAGGGAGAAGACACTGCGTCAAGCAGGTGCCCCGAATAACCGCTGGCGGGAGGAGCTCTCCCACATGAAGCGACTTCCCCCAGTGCTTCCCGGCCGCCCCTATGACCTGGCGGCGGCGACCGTGGCCACAGACCTGGAGAGCGGCGGAGCCGGTGCGGCTTGCGGCGGTAGCAACCTGGCGCCCCTACCTCGGAGAGAGACCGAGGAGTTCAACGATCTCCTGGACCTGGACTTTATTCTCTCCAATTCGCTGACCCATCCTCCGGAGTCAGTGGCCGCCACCGTGTCCTCGTCAGCGTCAGCCTCCTCTTCGTCGTCGCCGTCGAGCAGCGGCCCTGCCAGCGCGCCCTCCACCTGCAGCTTCACCTATCCGATCCGGGCCGGGAACGACCCGGGCGTGGCGCCGGGCGGCACGGGCGGAGGCCTCCTCTATGGCAGGGAGTCCGCTCCCCCTCCGACGGCTCCCTTCAACCTGGCGGACATCAACGACGTGAGCCCCTCGGGCGGCTTCGTGGCCGAGCTCCTGCGGCCAGAATTGGACCCGGTGTACATTCCGCCGCAGCAGCCGCAGCCGCCAGGTGGCGGGCTGATGGGCAAGTTCGTGCTGAAGGCGTCGCTGAGCGCCCCTGGCAGCGAGTACGGCAGCCCGTCGGTCATCAGCGTCAGCAAAGGCAGCCCTGACGGCAGCCACCCGGTGGTGGTGGCGCCCTACAACGGCGGGCCGCCGCGCACGTGCCCCAAGATCAAGCAGGAGGCGGTCTCTTCGTGCACCCACTTGGGCGCTGGACCCCCTCTCAGCAATGGCCACCGGCCGGCTGCACACGACTTCCCCCTGGGGCGGCAGCTCCCCAGCAGGACTACCCCGACCCTGGGTCTTGAGGAAGTGCTGAGCAGCAGGGACTGTCACCCTGCCCTGCCGCTTCCTCCCGGCTTCCATCCCCACCCGGGGCCCAATTACCCATCCTTCCTGCCCGATCAGATGCAGCCGCAAGTCCCGCCGCTCCATTACCAAGGTCAGTCCCGGGGATTTGTAGCTCGGGCTGGGGAGCCCTGTGTGTGCTGGCCCCACTTCGGGACACACGGGATGATGCTCACCCCACCTTCTTCACCCCTAGAGCTCATGCCACCCGGTTCCTGCATGCCAGAGGAGCCCAAGCCAAAGAGGGGAAGACGATCGTGGCCCCGGAAAAGGACCGCCACCCACACTTGTGATTACGCGGGCTGCGGCAAAACCTACACAAAGAGTTCCCATCTCAAGGCACACCTGCGAACCCACACAGGTGAGAAACCTTACCACTGTGACTGGGACGGCTGTGGATGGAAATTCGCCCGCTCAGATGAACTGACCAGGCACTACCGTAAACACACGGGGCACCGCCCGTTCCAGTGCCAAAAATGCGACCGAGCATTTTCCAGGTCGGACCACCTCGCCTTACACATGAAGAGGCATTTTTAA |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T81916-Ab | Anti-KLF4 monoclonal antibody |
| Target Antigen | GM-Tg-g-T81916-Ag | KLF4 protein |
| ORF Viral Vector | pGMLV000247 | Human KLF4 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000164 | Human KLF4 Adenovirus plasmid |
| ORF Viral Vector | pGMAD000806 | Human KLF4 Adenovirus plasmid |
| ORF Viral Vector | pGMPC001122 | Human KLF4 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLV000247 | Human KLF4 Lentivirus particle |
| ORF Viral Vector | vGMAD000164 | Human KLF4 Adenovirus particle |
| ORF Viral Vector | vGMAD000806 | Human KLF4 Adenovirus particle |
| ORF Viral Vector | pGMLV002172 | Human KLF4 Lentivirus plasmid |
| ORF Viral Vector | pGMLV002425 | Human KLF4 Lentivirus plasmid |
Target information
| Target ID | GM-T81916 |
| Target Name | KLF4 |
| Gene ID | 9314, 16600, 711169, 114505, 100379626, 481657, 520842, 100054047 |
| Gene Symbol and Synonyms | EZF,GKLF,KLF4,Zie |
| Uniprot Accession | O43474 |
| Uniprot Entry Name | KLF4_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000136826 |
| Target Classification | Tumor-associated antigen (TAA) |
This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
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