Human DNMT1/ADCADN/ AIM ORF/cDNA clone-Adenovirus particle (NM_001130823.2)

Pre-made Human DNMT1/ADCADN/ AIM Adenovirus for DNMT1 overexpression in-vitro and in-vivo. The DNMT1 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified DNMT1-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

Target products collectionGo to DNMT1/ADCADN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD000065 Human DNMT1 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD000065
Gene Name DNMT1
Accession Number NM_001130823.2
Gene ID 1786
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 4899 bp
Gene Alias ADCADN, AIM, CXXC9, DNMT, HSN1E, m.HsaI, MCMT
Fluorescent Reporter EGFP
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T88304-Ab Anti-DNMT1 monoclonal antibody
    Target Antigen GM-Tg-g-T88304-Ag DNMT1 protein
    ORF Viral Vector pGMAD000065 Human DNMT1 Adenovirus plasmid
    ORF Viral Vector pGMAD000673 Human DNMT1 Adenovirus plasmid
    ORF Viral Vector vGMAD000065 Human DNMT1 Adenovirus particle
    ORF Viral Vector vGMAD000673 Human DNMT1 Adenovirus particle


    Target information

    Target ID GM-T88304
    Target Name DNMT1
    Gene ID 1786, 13433, 574321, 84350, 101093502, 476715, 281119, 100058341
    Gene Symbol and Synonyms ADCADN,AIM,CXXC9,DNMT,DNMT1,Dnmt1o,HSN1E,m.HsaI,m.MmuI,MCMT,Met-1,Met1,MommeD2,MTase
    Uniprot Accession P26358
    Uniprot Entry Name DNMT1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000130816
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.