Recombinant multi-species DNMT1/ ADCADN/ AIM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNMT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: DNMT1, gene name: DNMT1, also named as ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT, m.HsaI. This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].

Order information

* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry

Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T88304-Ag-1	Human DNMT1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T88304-Ag-1	Rat DNMT1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T88304-Ag-1	Mouse DNMT1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T88304-Ag-1	Cynomolgus/ Rhesus macaque DNMT1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T88304-Ag-1	Feline DNMT1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T88304-Ag-1	Canine DNMT1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T88304-Ag-1	Bovine DNMT1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T88304-Ag-1	Equine DNMT1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T88304-Ag, GM-Tg-rg-T88304-Ag, GM-Tg-mg-T88304-Ag, GM-Tg-cynog-T88304-Ag, GM-Tg-felg-T88304-Ag, GM-Tg-cang-T88304-Ag, GM-Tg-bovg-T88304-Ag, GM-Tg-equg-T88304-Ag-1
Products Name	DNMT1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	DNMT1
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNMT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.