Human PLAU/ATF/ BDPLT5 ORF/cDNA clone-Adenovirus particle (NM_002658.4)

Pre-made Human PLAU/ATF/ BDPLT5 Adenovirus for PLAU overexpression in-vitro and in-vivo. The PLAU adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified PLAU-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

Target products collectionGo to PLAU/ATF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD000145 Human PLAU Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD000145
Gene Name PLAU
Accession Number NM_002658.4
Gene ID 5328
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 1296 bp
Gene Alias ATF, BDPLT5, QPD, u-PA, UPA, URK
Fluorescent Reporter
Mammalian Cell Selection Null
Fusion Tag Null
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T17758-Ab Anti-UROK/ PLAU/ ATF monoclonal antibody
    Target Antigen GM-Tg-g-T17758-Ag PLAU VLP (virus-like particle)
    ORF Viral Vector pGMAD000145 Human PLAU Adenovirus plasmid
    ORF Viral Vector vGMAD000145 Human PLAU Adenovirus particle


    Target information

    Target ID GM-T17758
    Target Name PLAU
    Gene ID 5328, 18792, 705853, 25619, 101098338, 403426, 281408, 100072886
    Gene Symbol and Synonyms ATF,BDPLT5,PLAU,QPD,u-PA,UPA,UPAM,URK
    Uniprot Accession P00749
    Uniprot Entry Name UROK_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Dent disease
    Gene Ensembl ENSG00000122861
    Target Classification Not Available

    This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.