Human LGR5/FEX/ GPR49 ORF/cDNA clone-Adenovirus particle (NM_003667.3)
Pre-made Human LGR5/FEX/ GPR49 Adenovirus for LGR5 overexpression in-vitro and in-vivo. The LGR5 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified LGR5-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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Product information
Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
vGMAD000158 | Human LGR5 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
5E+10PFU (1E+10pfu/ml×5ml) | |||
1E+11PFU (1E+10pfu/ml×10ml) | |||
Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMAD000158 |
Gene Name | LGR5 |
Accession Number | NM_003667.3 |
Gene ID | 8549 |
Species | Human |
Product Type | Adenovirus particle (overexpression) |
Insert Length | 2724 bp |
Gene Alias | FEX, GPR49, GPR67, GRP49, HG38 |
Fluorescent Reporter | ERFP |
Mammalian Cell Selection | |
Fusion Tag | Null |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Biosimilar | GMP-Bios-ab-440 | Pre-Made Petosemtamab biosimilar, Bispecific mAb, Anti-EGFR;LGR5 Antibody: Anti-ERBB/ERRP/HER1/mENA/ERBB1/PIG61/NISBD2;FEX/GPR49/GPR67/GRP49/HG38 therapeutic antibody |
Target Antibody | GM-Tg-g-T14231-Ab | Anti-LGR5/ FEX/ GPR49 monoclonal antibody |
Target Antigen | GM-Tg-g-T14231-Ag | LGR5 VLP (virus-like particle) |
ORF Viral Vector | pGMAD000158 | Human LGR5 Adenovirus plasmid |
ORF Viral Vector | vGMAD000158 | Human LGR5 Adenovirus particle |
ORF Viral Vector | pGMLV002254 | Human LGR5 Lentivirus plasmid |
Target information
Target ID | GM-T14231 |
Target Name | LGR5 |
Gene ID | 8549, 14160, 718661, 299802, 101080720, 609478, 520189, 100064565 |
Gene Symbol and Synonyms | FEX,GPR49,GPR67,GRP49,HG38,LGR5 |
Uniprot Accession | O75473 |
Uniprot Entry Name | LGR5_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, INN Index |
Disease | Cancer |
Gene Ensembl | ENSG00000139292 |
Target Classification | GPCR, Tumor-associated antigen (TAA) |
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.