Human DNMT3B/ICF/ ICF1 ORF/cDNA clone-Adenovirus particle (NM_006892.3)

Pre-made Human DNMT3B/ICF/ ICF1 Adenovirus for DNMT3B overexpression in-vitro and in-vivo. The DNMT3B adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified DNMT3B-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

Target products collectionGo to DNMT3B/ICF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD000196 Human DNMT3B Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD000196
Gene Name DNMT3B
Accession Number NM_006892.3
Gene ID 1789
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 2562 bp
Gene Alias ICF, ICF1, M.HsaIIIB
Fluorescent Reporter EGFP
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T65501-Ab Anti-DNMT3B monoclonal antibody
    Target Antigen GM-Tg-g-T65501-Ag DNMT3B protein
    ORF Viral Vector pGMAD000196 Human DNMT3B Adenovirus plasmid
    ORF Viral Vector vGMAD000196 Human DNMT3B Adenovirus particle
    ORF Viral Vector pGMLV002457 Human DNMT3B Lentivirus plasmid


    Target information

    Target ID GM-T65501
    Target Name DNMT3B
    Gene ID 1789, 13436, 711553, 444985, 101092926, 100685634, 353354, 100053900
    Gene Symbol and Synonyms DNMT3B,FSHD4,ICF,ICF1,M.HsaIIIB,MmuIIIB
    Uniprot Accession Q9UBC3
    Uniprot Entry Name DNM3B_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000088305
    Target Classification Tumor-associated antigen (TAA)

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.