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It's the GeneMedi's summary page for Target/Biomarker Introduction of KARS. The page also collects GeneMedi's different modalities and formats products for KARS in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the KARS target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Target IDGM-MP2574
Target NameKARS
Gene ID3735
Gene Official NameKARS
Gene AliasCMTRIB, DFNB891, KARS2, KRS, KARS
Protein Sub-locationTransmembrane Protein
Categorynull


Pre-made anti-KARS inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-KARS benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-KARS mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Cat No.Antibody NameFormatClassified by tagOrder
GM-Tg-hg-MP2574-AbAnti-KARS monoclonal antibodymabBiofunctional antibodymonoclonal antibody.




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