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It's the GeneMedi's summary page for Target/Biomarker Introduction of PDE4D. The page also collects GeneMedi's different modalities and formats products for PDE4D in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PDE4D target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]

Target IDGM-T02001
Target NamePDE4D
Gene ID5144
Gene Official NamePDE4D
Gene AliasACRDYS2, DPDE3, HSPDE4D, PDE43N2, STRK1, PDE4D
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target


Pre-made anti-PDE4D inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-PDE4D benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PDE4D mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Cat No.Antibody NameFormatClassified by tagOrder
GM-Tg-hg-T02001-AbAnti-PDE4D monoclonal antibodymabBiofunctional antibody, Therapeutics Target antibodymonoclonal antibody.




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