It's the GeneMedi's summary page for Target/Biomarker Introduction of ANO,ANO1. The page also collects GeneMedi's different modalities and formats products for ANO in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ANO target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

Enables calcium activated cation channel activity; intracellular calcium activated chloride channel activity; and iodide transmembrane transporter activity. Involved in cation transport; inorganic anion transport; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in apical plasma membrane and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Target IDGM-T05089
Target NameANO
Gene ID55107
Gene Official NameANO1
Gene AliasDOG1, ORAOV2, TAOS2, TMEM16A
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target

Pre-made anti-ANO inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-ANO benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ANO mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Cat No.Antibody NameFormatClassified by tagOrder
GM-Tg-hg-T05089-AbAnti-ANO/ANO1 monoclonal antibodymabBiofunctional antibody, Therapeutics Target antibodymonoclonal antibody.

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