CCN1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of CCN1. The page also collects GeneMedi's different modalities and formats products for CCN1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CCN1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011]

Target IDGM-T56505
Target NameCCN1
Gene ID3491,16007,83476,714970,479967,101100068,508941,100064066
Gene Symbol and SynonymsCCN1,CYR61,GIG1,IGFBP10
Uniprot AccessionO00622,Q9ES72
Uniprot Entry NameCCN1_HUMAN,CCN1_RAT
Protein Sub-locationSecreted Protein/Potential Cytokines
CategoryTherapeutics Target
DiseaseCancer
Gene EnsemblENSG00000142871
Target ClassificationTumor-associated antigen (TAA)


Pre-made anti-CCN1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-CCN1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CCN1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-CCN1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Recombinant multi-species CCN1/ CYR61/ GIG1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
CCN1 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made CCN1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP000491human CYR61 Lentivirus particleNM_001554HumanLentivirus particleDetail
pGMLP000491human CYR61 Lentivirus plasmidNM_001554HumanLentivirus plasmidDetail
vGMAP000008Human CYR61 Adenovirus particleBC001271HumanAdenovirus particleDetail
pGMAP000008Human CYR61 Adenovirus plasmidBC001271HumanAdenovirus plasmidDetail
pGMAD000547Norway rat Ccn1 Adenovirus plasmidNM_031327.2Norway RatAdenovirus plasmidDetail
vGMAD000547Norway rat Ccn1 Adenovirus particleNM_031327.2Norway RatAdenovirus particleDetail
pGMLPm002791mouse Cyr61 Lentivirus plasmidNM_010516MouseLentivirus plasmidDetail
vGMLPm002791mouse Cyr61 Lentivirus particleNM_010516MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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