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It's the GeneMedi's summary page for Target/Biomarker Introduction of HDAC4. The page also collects GeneMedi's different modalities and formats products for HDAC4 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HDAC4 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]

Target IDGM-T63816
Target NameHDAC4
Gene ID9759
Gene Official NameHDAC4
Gene AliasAHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target


Pre-made anti-HDAC4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.

Pre-made anti-HDAC4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HDAC4 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Cat No.Antibody NameFormatClassified by tagOrder
GM-Tg-hg-T63816-AbAnti-HDAC4 monoclonal antibodymabTherapeutics Target antibodymonoclonal antibody.




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