Recombinant multi-species HDAC4/ AHO3/ BDMR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: HDAC4, gene name: HDAC4, also named as AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].
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Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-T63816-Ag-1 | Human HDAC4 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T63816-Ag-1 | Rat HDAC4 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T63816-Ag-1 | Mouse HDAC4 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T63816-Ag-1 | Cynomolgus/ Rhesus macaque HDAC4 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-T63816-Ag-1 | Feline HDAC4 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-T63816-Ag-1 | Canine HDAC4 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T63816-Ag-1 | Bovine HDAC4 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-T63816-Ag-1 | Equine HDAC4 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-T63816-Ag, GM-Tg-rg-T63816-Ag, GM-Tg-mg-T63816-Ag, GM-Tg-cynog-T63816-Ag, GM-Tg-felg-T63816-Ag, GM-Tg-cang-T63816-Ag, GM-Tg-bovg-T63816-Ag, GM-Tg-equg-T63816-Ag-1 |
Products Name | HDAC4 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | HDAC4 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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