Recombinant multi-species HDAC4/ AHO3/ BDMR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HDAC4, gene name: HDAC4, also named as AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T63816-Ag-1Human HDAC4 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T63816-Ag-1Rat HDAC4 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T63816-Ag-1Mouse HDAC4 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T63816-Ag-1Cynomolgus/ Rhesus macaque HDAC4 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T63816-Ag-1Feline HDAC4 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T63816-Ag-1Canine HDAC4 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T63816-Ag-1Bovine HDAC4 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T63816-Ag-1Equine HDAC4 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T63816-Ag, GM-Tg-rg-T63816-Ag, GM-Tg-mg-T63816-Ag, GM-Tg-cynog-T63816-Ag,
GM-Tg-felg-T63816-Ag, GM-Tg-cang-T63816-Ag, GM-Tg-bovg-T63816-Ag, GM-Tg-equg-T63816-Ag-1
Products Name HDAC4 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameHDAC4
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.