CTSD: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of CTSD. The page also collects GeneMedi's different modalities and formats products for CTSD in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CTSD target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Target ID | GM-T67102 |
Target Name | CTSD |
Gene ID | 1509,13033,171293,703534,483662,101094625,282883,100629639 |
Gene Symbol and Synonyms | CatD,CD,CLN10,CPSD,CTSD,HEL-S-130P |
Uniprot Accession | P07339,P24268,Q4LAL9,P80209 |
Uniprot Entry Name | CATD_HUMAN,CATD_RAT,CATD_CANLF,CATD_BOVIN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | colorectal cancer, Malignant neoplasm of bladder |
Gene Ensembl | ENSG00000117984 |
Target Classification | N/A |
Pre-made anti-CTSD inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-CTSD benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CTSD mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-CTSD monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Recombinant multi-species CATD/ CTSD/ CLN10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CTSD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
CTSD protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made CTSD viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMAP000223 | Human CTSD Adenovirus plasmid | BC016320 | Human | Adenovirus plasmid | Detail |
pGMLP000108 | human CTSD Lentivirus plasmid | NM_001909 | Human | Lentivirus plasmid | Detail |
vGMAP000192 | Human CTSD Adenovirus particle | BC016320 | Human | Adenovirus particle | Detail |
vGMLP000108 | human CTSD Lentivirus particle | NM_001909 | Human | Lentivirus particle | Detail |
vGMAP000223 | Human CTSD Adenovirus particle | BC016320 | Human | Adenovirus particle | Detail |
pGMAP000192 | Human CTSD Adenovirus plasmid | BC016320 | Human | Adenovirus plasmid | Detail |
pGMLPm002184 | mouse Ctsd Lentivirus plasmid | NM_009983 | Mouse | Lentivirus plasmid | Detail |
vGMLPm002184 | mouse Ctsd Lentivirus particle | NM_009983 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.