D2R/DRD2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of D2R/DRD2. The page also collects GeneMedi's different modalities and formats products for D2R in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the D2R target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
|Gene Symbol and Synonyms||D2DR,D2R,Drd-2,DRD2|
|Uniprot Entry Name||DRD2_HUMAN,DRD2_RAT,DRD2_CANLF,DRD2_BOVIN|
|Protein Sub-location||Transmembrane Protein|
|Target Classification||GPCR, Tumor-associated antigen (TAA)|
Pre-made anti-D2R inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-D2R benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-D2R mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
|Antibody Name||Species||Format||Classified by tag||Detail|
|Anti-D2R/DRD2 monoclonal antibody||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||mab||FACS/Biofunctional Antibody, Therapeutics Target antibody||Detail|
Multi-species DRD2/ D2R/ D2DR VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine D2R/DRD2 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
|Products Name||Species||Expression Platform||Detail|
|D2R/DRD2 VLP (virus-like particle)||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||Mammalian cell||Products Developing|
Pre-made DRD2 viral vector in GM Promise-ORFTM
|Cat No.||Products name||NM ID||Species||Type||Detail|
|vGMAP000308||Human DRD2 Adenovirus particle||BC021195||Human||Adenovirus particle||Detail|
|vGMLV000444||human DRD2 Lentivirus particle||NM_000795.3||Human||Lentivirus particle||Detail|
|pGMLV000466||human DRD2 Lentivirus plasmid||NM_000795.3||Human||Lentivirus plasmid||Detail|
|pGMLV000806||human DRD2 Lentivirus plasmid||NM_000795.3||Human||Lentivirus plasmid||Detail|
|vGMLV000806||human DRD2 Lentivirus particle||NM_000795.3||Human||Lentivirus particle||Detail|
|pGMAP000308||Human DRD2 Adenovirus plasmid||BC021195||Human||Adenovirus plasmid||Detail|
|pGMLV000444||human DRD2 Lentivirus plasmid||NM_000795.3||Human||Lentivirus plasmid||Detail|
|vGMLV000466||human DRD2 Lentivirus particle||NM_000795.3||Human||Lentivirus particle||Detail|
|pGMLPm005196||mouse Drd2 Lentivirus plasmid||XM_006509996.3||Mouse||Lentivirus plasmid||Detail|
|vGMLPm005196||mouse Drd2 Lentivirus particle||XM_006509996.3||Mouse||Lentivirus particle||Detail|
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.