ESR2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of ESR2. The page also collects GeneMedi's different modalities and formats products for ESR2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ESR2 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]

Target IDGM-T80896
Target NameESR2
Gene ID2100,13983,25149,574110,403639,101086317,281146,100033964
Gene Symbol and Synonymser,ER-BETA,Erb,Erb2,ERbeta,ER[b],ESR-BETA,ESR2,ESRB,ESTRB,NR3A2,ODG8
Uniprot AccessionQ92731,Q62986,Q9TTE5,Q9XSB5
Uniprot Entry NameESR2_HUMAN,ESR2_MACMU,ESR2_RAT,ESR2_BOVIN
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseCancer
Gene EnsemblENSG00000140009
Target ClassificationTumor-associated antigen (TAA)


Pre-made anti-ESR2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-ESR2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ESR2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-ESR2 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species ESR2/ ER-BETA/ ESR-BETA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ESR2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
ESR2 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made ESR2 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP001497human ESR2 Lentivirus particleNM_001437HumanLentivirus particleDetail
vGMLV000848human ESR2 Lentivirus particleNM_001040275.1HumanLentivirus particleDetail
pGMLV000848human ESR2 Lentivirus plasmidNM_001040275.1HumanLentivirus plasmidDetail
pGMLP001497human ESR2 Lentivirus plasmidNM_001437HumanLentivirus plasmidDetail
pGMLPm005127mouse Esr2 Lentivirus plasmidNM_010157.3MouseLentivirus plasmidDetail
pGMLPm005128mouse Esr2 Lentivirus plasmidNM_207707.1MouseLentivirus plasmidDetail
vGMLPm005127mouse Esr2 Lentivirus particleNM_010157.3MouseLentivirus particleDetail
vGMLPm005128mouse Esr2 Lentivirus particleNM_207707.1MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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