ESR2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of ESR2. The page also collects GeneMedi's different modalities and formats products for ESR2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ESR2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
|Gene Symbol and Synonyms||er,ER-BETA,Erb,Erb2,ERbeta,ER[b],ESR-BETA,ESR2,ESRB,ESTRB,NR3A2,ODG8|
|Uniprot Entry Name||ESR2_HUMAN,ESR2_MACMU,ESR2_RAT,ESR2_BOVIN|
|Protein Sub-location||Introcelluar Protein|
|Target Classification||Tumor-associated antigen (TAA)|
Pre-made anti-ESR2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-ESR2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ESR2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
|Antibody Name||Species||Format||Classified by tag||Detail|
|Anti-ESR2 monoclonal antibody||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||mab||Therapeutics Target antibody||Detail|
Recombinant multi-species ESR2/ ER-BETA/ ESR-BETA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ESR2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
|Products Name||Species||Expression Platform||Detail|
|ESR2 protein||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||Mammalian cell||Detail|
Pre-made ESR2 viral vector in GM Promise-ORFTM
|Cat No.||Products name||NM ID||Species||Type||Detail|
|vGMLP001497||human ESR2 Lentivirus particle||NM_001437||Human||Lentivirus particle||Detail|
|vGMLV000848||human ESR2 Lentivirus particle||NM_001040275.1||Human||Lentivirus particle||Detail|
|pGMLV000848||human ESR2 Lentivirus plasmid||NM_001040275.1||Human||Lentivirus plasmid||Detail|
|pGMLP001497||human ESR2 Lentivirus plasmid||NM_001437||Human||Lentivirus plasmid||Detail|
|pGMLPm005127||mouse Esr2 Lentivirus plasmid||NM_010157.3||Mouse||Lentivirus plasmid||Detail|
|pGMLPm005128||mouse Esr2 Lentivirus plasmid||NM_207707.1||Mouse||Lentivirus plasmid||Detail|
|vGMLPm005127||mouse Esr2 Lentivirus particle||NM_010157.3||Mouse||Lentivirus particle||Detail|
|vGMLPm005128||mouse Esr2 Lentivirus particle||NM_207707.1||Mouse||Lentivirus particle||Detail|
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.