TRPV1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of TRPV1. The page also collects GeneMedi's different modalities and formats products for TRPV1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the TRPV1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]

Target IDGM-T83193
Target NameTRPV1
Gene ID7442,193034,83810,721455,445457,101093406,107131508,100034158
Gene Symbol and SynonymsOTRPC1,TRPV1,TRPV1alpha,TRPV1beta,TRPV1_SON,VR-1,VR.5'sv,VR1,Vr1l1
Uniprot AccessionQ8NER1,O35433,Q697L1
Uniprot Entry NameTRPV1_HUMAN,TRPV1_RAT,TRPV1_CANLF
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target
DiseaseN/A
Gene EnsemblENSG00000196689
Target ClassificationIon Channel


Pre-made anti-TRPV1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-TRPV1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TRPV1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-TRPV1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Multi-species TRPV1/ VR1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TRPV1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
TRPV1 VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made TRPV1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLV000632human TRPV1 Lentivirus particleNM_080704.3HumanLentivirus particleDetail
pGMLV000632human TRPV1 Lentivirus plasmidNM_080704.3HumanLentivirus plasmidDetail
vGMLP002884human TRPV1 Lentivirus particleNM_080704HumanLentivirus particleDetail
pGMLP002884human TRPV1 Lentivirus plasmidNM_080704HumanLentivirus plasmidDetail
pGMLV000436mouse Trpv1 Lentivirus plasmidNM_001001445.2MouseLentivirus plasmidDetail
pGMAD000590house mouse Trpv1 Adenovirus plasmidNM_001001445.2House MouseAdenovirus plasmidDetail
pGMAAV000088rat Trpv1 AAV plasmidNM_031982.1RatAAV plasmidDetail
vGMLV000436mouse Trpv1 Lentivirus particleNM_001001445.2MouseLentivirus particleDetail
vGMAD000590house mouse Trpv1 Adenovirus particleNM_001001445.2House MouseAdenovirus particleDetail
vGMAAV000088rat Trpv1 AAV particleNM_031982.1RatAAV particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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