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Human CXCL12/IRH/ PBSF ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_000609)
Pre-made Human CXCL12/IRH/ PBSF Adeno-associated virus expression plasmid (ITR-vector) for CXCL12 AAV packaging, CXCL12 AAV production.The purified Human CXCL12/IRH/ PBSF AAV particle serves as an invaluable asset for in-depth in vivo CXCL12 studies, mechanism of action (MOA) research, and the evolution of CXCL12-associated gene therapy strategies.
Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.
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Product information
| Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
|---|---|---|---|
| pGMAAV000139 | Human CXCL12 Adeno-associate virus(AAV) plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
| GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
| High Quality (HQ) Grade | |||
| Seed | 5ug |
Product Description
| Catalog ID | pGMAAV000139 |
| Gene Name | CXCL12 |
| Accession Number | NM_000609 |
| Gene ID | 6387 |
| Species | Human |
| Product Type | Adeno-associate virus(AAV) plasmid (overexpression) |
| Insert Length | 282 bp |
| Gene Alias | IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1 |
| Fluorescent Reporter | EGFP |
| Mammalian Cell Selection | |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T04773-Ab | Anti-SDF1/ CXCL12/ IRH functional antibody |
| Target Antigen | GM-Tg-g-T04773-Ag | CXCL12 protein |
| Cytokine | cks-Tg-g-GM-T04773 | chemokine (C-X-C motif) ligand 12 (CXCL12) protein & antibody |
| ORF Viral Vector | pGMLV000007 | Human CXCL12 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000955 | Human CXCL12 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000581 | Human CXCL12 Adenovirus plasmid |
| ORF Viral Vector | pGMAAV000139 | Human CXCL12 Adeno-associate virus(AAV) plasmid |
| ORF Viral Vector | pGMAP000581 | Human CXCL12 Adenovirus plasmid |
| ORF Viral Vector | vGMLV000007 | Human CXCL12 Lentivirus particle |
| ORF Viral Vector | vGMLV000955 | Human CXCL12 Lentivirus particle |
| ORF Viral Vector | vGMAD000581 | Human CXCL12 Adenovirus particle |
| ORF Viral Vector | vGMAAV000139 | Human CXCL12 Adeno-associate virus(AAV) particle |
| ORF Viral Vector | vGMAP000581 | Human CXCL12 Adenovirus particle |
| ORF Viral Vector | pGMLV002285 | Human CXCL12 Lentivirus plasmid |
Target information
| Target ID | GM-T04773 |
| Target Name | CXCL12 |
| Gene ID | 6387, 20315, 574334, 24772, 493806, 449622, 613811, 100049872 |
| Gene Symbol and Synonyms | CXCL12,IRH,PBSF,SCYB12,SDF-1,SDF1,TLSF,TPAR1 |
| Uniprot Accession | P48061 |
| Uniprot Entry Name | SDF1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Immuno-oncology Target, Cytokine Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000107562 |
| Target Classification | Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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