Human ATP2A2/ATP2B/ DAR ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_170665)

Pre-made Human ATP2A2/ATP2B/ DAR Adeno-associated virus expression plasmid (ITR-vector) for ATP2A2 AAV packaging, ATP2A2 AAV production.The purified Human ATP2A2/ATP2B/ DAR AAV particle serves as an invaluable asset for in-depth in vivo ATP2A2 studies, mechanism of action (MOA) research, and the evolution of ATP2A2-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

Target products collectionGo to ATP2A2/ATP2B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMAAV000157 Human ATP2A2 Adeno-associate virus(AAV) plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMAAV000157
Gene Name ATP2A2
Accession Number NM_170665
Gene ID 488
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 3129 bp
Gene Alias ATP2B, DAR, DD, SERCA2
Fluorescent Reporter EGFP
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0055-Ab Anti-ATP2A2 monoclonal antibody
    Target Antigen GM-Tg-g-IP0055-Ag ATP2A2 protein
    ORF Viral Vector pGMAD000382 Human ATP2A2 Adenovirus plasmid
    ORF Viral Vector pGMAD000481 Human ATP2A2 Adenovirus plasmid
    ORF Viral Vector pGMAAV000157 Human ATP2A2 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAP000495 Human ATP2A2 Adenovirus plasmid
    ORF Viral Vector vGMAD000382 Human ATP2A2 Adenovirus particle
    ORF Viral Vector vGMAD000481 Human ATP2A2 Adenovirus particle
    ORF Viral Vector vGMAAV000157 Human ATP2A2 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAP000495 Human ATP2A2 Adenovirus particle


    Target information

    Target ID GM-IP0055
    Target Name ATP2A2
    Gene ID 488, 11938, 710702, 29693, 493691, 403878, 540568, 791242
    Gene Symbol and Synonyms 9530097L16Rik,ATP2A2,ATP2B,D5Wsu150e,DAR,DD,mKIAA4195,SERCA2,Serca2a,SERCA2B,SercaII
    Uniprot Accession P16615
    Uniprot Entry Name AT2A2_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000174437
    Target Classification Not Available

    This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.