Recombinant multi-species AT2A2/ ATP2A2/ ATP2B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP2A2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ATP2A2, gene name: ATP2A2, also named as ATP2B, DAR, DD, SERCA2. This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-IP0055-Ag-1	Human ATP2A2 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-IP0055-Ag-1	Rat ATP2A2 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-IP0055-Ag-1	Mouse ATP2A2 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-IP0055-Ag-1	Cynomolgus/ Rhesus macaque ATP2A2 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-IP0055-Ag-1	Feline ATP2A2 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-IP0055-Ag-1	Canine ATP2A2 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP0055-Ag-1	Bovine ATP2A2 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP0055-Ag-1	Equine ATP2A2 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-IP0055-Ag, GM-Tg-rg-IP0055-Ag, GM-Tg-mg-IP0055-Ag, GM-Tg-cynog-IP0055-Ag, GM-Tg-felg-IP0055-Ag, GM-Tg-cang-IP0055-Ag, GM-Tg-bovg-IP0055-Ag, GM-Tg-equg-IP0055-Ag-1
Products Name	ATP2A2 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	ATP2A2
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATP2A2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.