Human TLR5/MELIOS/ SLE1 ORF/cDNA clone-Adenovirus plasmid (NM_003268)

Pre-made Human TLR5/MELIOS/ SLE1 adenoviral expression plasmid for TLR5 adenovirus packaging, TLR5 adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

Target products collectionGo to TLR5/MELIOS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMAD000152 Human TLR5 Adenovirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMAD000152
Gene Name TLR5
Accession Number NM_003268
Gene ID 7100
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 2577 bp
Gene Alias MELIOS, SLE1, SLEB1, TIL3
Fluorescent Reporter
Mammalian Cell Selection Null
Fusion Tag Null
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T43718-Ab Anti-TLR5/ MELIOS/ SLE1 monoclonal antibody
    Target Antigen GM-Tg-g-T43718-Ag TLR5 VLP (virus-like particle)
    ORF Viral Vector pGMAD000152 Human TLR5 Adenovirus plasmid
    ORF Viral Vector pGMLP003189 Human TLR5 Lentivirus plasmid
    ORF Viral Vector vGMAD000152 Human TLR5 Adenovirus particle
    ORF Viral Vector vGMLP003189 Human TLR5 Lentivirus particle


    Target information

    Target ID GM-T43718
    Target Name TLR5
    Gene ID 7100, 53791, 574328, 289337, 101082202, 488605, 444870, 111771347
    Gene Symbol and Synonyms MELIOS,SLE1,SLEB1,TIL3,TLR-5,TLR5
    Uniprot Accession O60602
    Uniprot Entry Name TLR5_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease Not Available
    Gene Ensembl ENSG00000187554
    Target Classification Checkpoint-Immuno Oncology

    This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.