Human TLR5/MELIOS/ SLE1 ORF/cDNA clone-Adenovirus particle (NM_003268)
Pre-made Human TLR5/MELIOS/ SLE1 Adenovirus for TLR5 overexpression in-vitro and in-vivo. The TLR5 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified TLR5-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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Product information
Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
vGMAD000152 | Human TLR5 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
5E+10PFU (1E+10pfu/ml×5ml) | |||
1E+11PFU (1E+10pfu/ml×10ml) | |||
Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMAD000152 |
Gene Name | TLR5 |
Accession Number | NM_003268 |
Gene ID | 7100 |
Species | Human |
Product Type | Adenovirus particle (overexpression) |
Insert Length | 2577 bp |
Gene Alias | MELIOS, SLE1, SLEB1, TIL3 |
Fluorescent Reporter | |
Mammalian Cell Selection | Null |
Fusion Tag | Null |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T43718-Ab | Anti-TLR5/ MELIOS/ SLE1 monoclonal antibody |
Target Antigen | GM-Tg-g-T43718-Ag | TLR5 VLP (virus-like particle) |
ORF Viral Vector | pGMAD000152 | Human TLR5 Adenovirus plasmid |
ORF Viral Vector | pGMLP003189 | Human TLR5 Lentivirus plasmid |
ORF Viral Vector | vGMAD000152 | Human TLR5 Adenovirus particle |
ORF Viral Vector | vGMLP003189 | Human TLR5 Lentivirus particle |
Target information
Target ID | GM-T43718 |
Target Name | TLR5 |
Gene ID | 7100, 53791, 574328, 289337, 101082202, 488605, 444870, 111771347 |
Gene Symbol and Synonyms | MELIOS,SLE1,SLEB1,TIL3,TLR-5,TLR5 |
Uniprot Accession | O60602 |
Uniprot Entry Name | TLR5_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Immuno-oncology Target |
Disease | Not Available |
Gene Ensembl | ENSG00000187554 |
Target Classification | Checkpoint-Immuno Oncology |
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.