Human PSCA/PRO232 ORF/cDNA clone-Lentivirus plasmid (NM_005672)
Cat. No.: pGMLP000992
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human PSCA/PRO232 Lentiviral expression plasmid for PSCA lentivirus packaging, PSCA lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.
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Product Description
Catalog ID | pGMLP000992 |
Gene Name | PSCA |
Accession Number | NM_005672 |
Gene ID | 8000 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 345 bp |
Gene Alias | PRO232 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGGCAGGCTTGGCCCTGCAGCCAGGCACTGCCCTGCTGTGCTACTCCTGCAAAGCCCAGGTGAGCAACGAGGACTGCCTGCAGGTGGAGAACTGCACCCAGCTGGGGGAGCAGTGCTGGACCGCGCGCATCCGCGCAGTTGGCCTCCTGACCGTCATCAGCAAAGGCTGCAGCTTGAACTGCGTGGATGACTCACAGGACTACTACGTGGGCAAGAAGAACATCACGTGCTGTGACACCGACTTGTGCAACGCCAGCGGGGCCCATGCCCTGCAGCCGGCTGCTGCCATCCTTGCGCTGCTCCCTGCACTCGGCCTGCTGCTCTGGGGACCCGGCCAGCTCTAG |
ORF Protein Sequence | MAGLALQPGTALLCYSCKAQVSNEDCLQVENCTQLGEQCWTARIRAVGLLTVISKGCSLNCVDDSQDYYVGKKNITCCDTDLCNASGAHALQPAAAILALLPALGLLLWGPGQL |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T23953-Ab | Anti-PSCA/ PRO232 monoclonal antibody |
Target Antigen | GM-Tg-g-T23953-Ag | PSCA VLP (virus-like particle) |
ORF Viral Vector | pGMLP000992 | Human PSCA Lentivirus plasmid |
ORF Viral Vector | pGMLP001836 | Human PSCA Lentivirus plasmid |
ORF Viral Vector | vGMLP000992 | Human PSCA Lentivirus particle |
ORF Viral Vector | vGMLP001836 | Human PSCA Lentivirus particle |
Target information
Target ID | GM-T23953 |
Target Name | PSCA |
Gene ID | 8000, 72373, 703505, 680210, 101097300, 482068, 100298702, 100063721 |
Gene Symbol and Synonyms | 2210408B04Rik,lncPSCA,PRO232,PSCA |
Uniprot Accession | O43653 |
Uniprot Entry Name | PSCA_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Immuno-oncology Target |
Disease | Prostate Cancer, Type 2 diabetes mellitus with diabetic nephropathy |
Gene Ensembl | ENSG00000167653 |
Target Classification | Checkpoint-Immuno Oncology |
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
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