Human PSCA/PRO232 ORF/cDNA clone-Lentivirus plasmid (NM_005672)

Cat. No.: pGMLP001836
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PSCA/PRO232 Lentiviral expression plasmid for PSCA lentivirus packaging, PSCA lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP001836
Gene Name PSCA
Accession Number NM_005672
Gene ID 8000
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 345 bp
Gene Alias PRO232
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCAGGCTTGGCCCTGCAGCCAGGCACTGCCCTGCTGTGCTACTCCTGCAAAGCCCAGGTGAGCAACGAGGACTGCCTGCAGGTGGAGAACTGCACCCAGCTGGGGGAGCAGTGCTGGACCGCGCGCATCCGCGCAGTTGGCCTCCTGACCGTCATCAGCAAAGGCTGCAGCTTGAACTGCGTGGATGACTCACAGGACTACTACGTGGGCAAGAAGAACATCACGTGCTGTGACACCGACTTGTGCAACGCCAGCGGGGCCCATGCCCTGCAGCCGGCTGCTGCCATCCTTGCGCTGCTCCCTGCACTCGGCCTGCTGCTCTGGGGACCCGGCCAGCTCTAG
ORF Protein Sequence MAGLALQPGTALLCYSCKAQVSNEDCLQVENCTQLGEQCWTARIRAVGLLTVISKGCSLNCVDDSQDYYVGKKNITCCDTDLCNASGAHALQPAAAILALLPALGLLLWGPGQL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T23953-Ab Anti-PSCA/ PRO232 monoclonal antibody
    Target Antigen GM-Tg-g-T23953-Ag PSCA VLP (virus-like particle)
    ORF Viral Vector pGMLP000992 Human PSCA Lentivirus plasmid
    ORF Viral Vector pGMLP001836 Human PSCA Lentivirus plasmid
    ORF Viral Vector vGMLP000992 Human PSCA Lentivirus particle
    ORF Viral Vector vGMLP001836 Human PSCA Lentivirus particle


    Target information

    Target ID GM-T23953
    Target Name PSCA
    Gene ID 8000, 72373, 703505, 680210, 101097300, 482068, 100298702, 100063721
    Gene Symbol and Synonyms 2210408B04Rik,lncPSCA,PRO232,PSCA
    Uniprot Accession O43653
    Uniprot Entry Name PSCA_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease Prostate Cancer, Type 2 diabetes mellitus with diabetic nephropathy
    Gene Ensembl ENSG00000167653
    Target Classification Checkpoint-Immuno Oncology

    This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]



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