Human PNOC/N/OFQ/NOP ORF/cDNA clone-Lentivirus plasmid (NM_006228)

Cat. No.: pGMLP003008
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PNOC/N/OFQ/NOP Lentiviral expression plasmid for PNOC lentivirus packaging, PNOC lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.


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Product Description

Catalog ID pGMLP003008
Gene Name PNOC
Accession Number NM_006228
Gene ID 5368
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 531 bp
Gene Alias N/OFQ,NOP,OFQ,ppN/OFQ,PPNOC
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAAAGTCCTGCTTTGTGACCTGCTGCTGCTCAGTCTCTTCTCCAGTGTGTTCAGCAGTTGTCAGAGGGACTGTCTCACATGCCAGGAGAAGCTCCACCCAGCCCTGGACAGCTTCGACCTGGAGGTGTGCATCCTCGAGTGTGAAGAGAAGGTCTTCCCCAGCCCCCTCTGGACTCCATGCACCAAGGTCATGGCCAGGAGCTCTTGGCAGCTCAGCCCTGCCGCCCCAGAGCATGTGGCGGCTGCTCTCTACCAGCCGAGAGCTTCGGAGATGCAGCATCTGCGGCGAATGCCCCGAGTCCGGAGCTTGTTCCAGGAGCAGGAAGAGCCCGAGCCTGGCATGGAGGAGGCTGGTGAGATGGAGCAGAAGCAGCTGCAGAAGAGATTTGGGGGCTTCACCGGGGCCCGGAAGTCGGCCAGGAAGTTGGCCAATCAGAAGCGGTTCAGTGAGTTTATGAGGCAATACTTGGTCCTGAGCATGCAGTCCAGCCAGCGCCGGCGCACCCTGCACCAGAATGGTAATGTGTAG
ORF Protein Sequence MKVLLCDLLLLSLFSSVFSSCQRDCLTCQEKLHPALDSFDLEVCILECEEKVFPSPLWTPCTKVMARSSWQLSPAAPEHVAAALYQPRASEMQHLRRMPRVRSLFQEQEEPEPGMEEAGEMEQKQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQRRRTLHQNGNV

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2561-Ab Anti-PNOC/ N/OFQ/ NOP monoclonal antibody
    Target Antigen GM-Tg-g-MP2561-Ag PNOC VLP (virus-like particle)
    ORF Viral Vector pGMLP003008 Human PNOC Lentivirus plasmid
    ORF Viral Vector vGMLP003008 Human PNOC Lentivirus particle


    Target information

    Target ID GM-MP2561
    Target Name PNOC
    Gene ID 5368, 18155, 713633, 25516, 101094754, 486095, 281414, 100061049
    Gene Symbol and Synonyms N/OFQ,N23K,Nociceptin,NOP,Npnc1,OFQ,OFQ/N,PNOC,ppN/OFQ,PPNOC
    Uniprot Accession Q13519
    Uniprot Entry Name PNOC_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000168081
    Target Classification Not Available

    This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include nociceptin, nocistatin, and orphanin FQ2 (OFQ2). Nociceptin, also known as orphanin FQ, is a 17-amino acid neuropeptide that binds to the nociceptin receptor to induce increased pain sensitivity, and may additionally regulate body temperature, learning and memory, and hunger. Another product of the encoded preproprotein, nocistatin, may inhibit the effects of nociceptin. [provided by RefSeq, Jul 2015]



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