Human IL5/EDF/ IL-5 ORF/cDNA clone-Lentivirus plasmid (NM_000879)
Pre-made Human IL5/EDF/ IL-5 Lentiviral expression plasmid for IL5 lentivirus packaging, IL5 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMLP004769 | Human IL5 Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMLP004769 |
Gene Name | IL5 |
Accession Number | NM_000879 |
Gene ID | 3567 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 405 bp |
Gene Alias | EDF, IL-5, TRF |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Sequence | ATGAGGATGCTTCTGCATTTGAGTTTGCTAGCTCTTGGAGCTGCCTACGTGTATGCCATCCCCACAGAAATTCCCACAAGTGCATTGGTGAAAGAGACCTTGGCACTGCTTTCTACTCATCGAACTCTGCTGATAGCCAATGAGACTCTGAGGATTCCTGTTCCTGTACATAAAAATCACCAACTGTGCACTGAAGAAATCTTTCAGGGAATAGGCACACTGGAGAGTCAAACTGTGCAAGGGGGTACTGTGGAAAGACTATTCAAAAACTTGTCCTTAATAAAGAAATACATTGACGGCCAAAAAAAAAAGTGTGGAGAAGAAAGACGGAGAGTAAACCAATTCCTAGACTACCTGCAAGAGTTTCTTGGTGTAATGAACACCGAGTGGATAATAGAAAGTTGA |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Biosimilar | GMP-Bios-ab-479 | Pre-Made Reslizumab biosimilar, Whole mAb, Anti-IL5 Antibody: Anti-EDF/IL-5/TRF therapeutic antibody |
Biosimilar | GMP-Bios-ab-142 | Pre-Made Depemokimab biosimilar, Whole mAb, Anti-IL5 Antibody: Anti-EDF/IL-5/TRF therapeutic antibody |
Biosimilar | GMP-Bios-ab-341 | Pre-Made Mepolizumab biosimilar, Whole mAb, Anti-IL5 Antibody: Anti-EDF/IL-5/TRF therapeutic antibody |
Target Antibody | GM-Tg-g-T78585-Ab | Anti-IL5/ EDF/ IL-5 functional antibody |
Target Antigen | GM-Tg-g-T78585-Ag | IL5 protein |
ORF Viral Vector | pGMLP004769 | Human IL5 Lentivirus plasmid |
ORF Viral Vector | pGMLP-IL-008 | Human IL5 Lentivirus plasmid |
ORF Viral Vector | pGMAP-IL-091 | Human IL5 Adenovirus plasmid |
ORF Viral Vector | vGMLP004769 | Human IL5 Lentivirus particle |
ORF Viral Vector | vGMLP-IL-008 | Human IL5 Lentivirus particle |
ORF Viral Vector | vGMAP-IL-091 | Human IL5 Adenovirus particle |
Target information
Target ID | GM-T78585 |
Target Name | IL5 |
Gene ID | 3567, 16191, 710622, 24497, 493803, 403790, 280825, 100034199 |
Gene Symbol and Synonyms | EDF,IL-5,IL5,TRF |
Uniprot Accession | P05113 |
Uniprot Entry Name | IL5_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target, INN Index |
Disease | Hodgkin's disease, Overactive bladder |
Gene Ensembl | ENSG00000113525 |
Target Classification | Not Available |
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
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