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Human IL5/EDF/ IL-5 ORF/cDNA clone-Lentivirus particle (NM_000879)
Pre-made Human IL5/EDF/ IL-5 Lentiviral expression plasmid for IL5 lentivirus packaging, IL5 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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Product information
| Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
|---|---|---|---|
| vGMLP004769 | Human IL5 Lentivirus particle | Pilot Grade | 1.0E+8TU |
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| Research Grade | 1.0E+8TU | ||
| 5.0E+8TU | |||
| 1.0E+9TU | |||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMLP004769 |
| Gene Name | IL5 |
| Accession Number | NM_000879 |
| Gene ID | 3567 |
| Species | Human |
| Product Type | Lentivirus particle (overexpression) |
| Insert Length | 405 bp |
| Gene Alias | EDF, IL-5, TRF |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| Sequence | ATGAGGATGCTTCTGCATTTGAGTTTGCTAGCTCTTGGAGCTGCCTACGTGTATGCCATCCCCACAGAAATTCCCACAAGTGCATTGGTGAAAGAGACCTTGGCACTGCTTTCTACTCATCGAACTCTGCTGATAGCCAATGAGACTCTGAGGATTCCTGTTCCTGTACATAAAAATCACCAACTGTGCACTGAAGAAATCTTTCAGGGAATAGGCACACTGGAGAGTCAAACTGTGCAAGGGGGTACTGTGGAAAGACTATTCAAAAACTTGTCCTTAATAAAGAAATACATTGACGGCCAAAAAAAAAAGTGTGGAGAAGAAAGACGGAGAGTAAACCAATTCCTAGACTACCTGCAAGAGTTTCTTGGTGTAATGAACACCGAGTGGATAATAGAAAGTTGA |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Biosimilar | GMP-Bios-ab-479 | Pre-Made Reslizumab biosimilar, Whole mAb, Anti-IL5 Antibody: Anti-EDF/IL-5/TRF therapeutic antibody |
| Biosimilar | GMP-Bios-ab-142 | Pre-Made Depemokimab biosimilar, Whole mAb, Anti-IL5 Antibody: Anti-EDF/IL-5/TRF therapeutic antibody |
| Biosimilar | GMP-Bios-ab-341 | Pre-Made Mepolizumab biosimilar, Whole mAb, Anti-IL5 Antibody: Anti-EDF/IL-5/TRF therapeutic antibody |
| Target Antibody | GM-Tg-g-T78585-Ab | Anti-IL5/ EDF/ IL-5 functional antibody |
| Target Antigen | GM-Tg-g-T78585-Ag | IL5 protein |
| ORF Viral Vector | pGMLP004769 | Human IL5 Lentivirus plasmid |
| ORF Viral Vector | pGMLP-IL-008 | Human IL5 Lentivirus plasmid |
| ORF Viral Vector | pGMAP-IL-091 | Human IL5 Adenovirus plasmid |
| ORF Viral Vector | vGMLP004769 | Human IL5 Lentivirus particle |
| ORF Viral Vector | vGMLP-IL-008 | Human IL5 Lentivirus particle |
| ORF Viral Vector | vGMAP-IL-091 | Human IL5 Adenovirus particle |
Target information
| Target ID | GM-T78585 |
| Target Name | IL5 |
| Gene ID | 3567, 16191, 710622, 24497, 493803, 403790, 280825, 100034199 |
| Gene Symbol and Synonyms | EDF,IL-5,IL5,TRF |
| Uniprot Accession | P05113 |
| Uniprot Entry Name | IL5_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, INN Index |
| Disease | Hodgkin's disease, Overactive bladder |
| Gene Ensembl | ENSG00000113525 |
| Target Classification | Not Available |
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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