Human ROCK1/P160ROCK/ ROCK-I ORF/cDNA clone-Lentivirus plasmid (NM_005406.2)

Pre-made Human ROCK1/P160ROCK/ ROCK-I Lentiviral expression plasmid for ROCK1 lentivirus packaging, ROCK1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collectionGo to ROCK1/P160ROCK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000212 Human ROCK1 Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug

Product Description

Catalog ID pGMLV000212
Gene Name ROCK1
Accession Number NM_005406.2
Gene ID 6093
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 4065 bp
Gene Alias P160ROCK, ROCK-I
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin


    Data / case study

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    Associated products

    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T51282-Ab Anti-ROCK1 monoclonal antibody
    Target Antigen GM-Tg-g-T51282-Ag ROCK1 protein
    ORF Viral Vector pGMLV000212 Human ROCK1 Lentivirus plasmid
    ORF Viral Vector vGMLV000212 Human ROCK1 Lentivirus particle

    Target information

    Target ID GM-T51282
    Target Name ROCK1
    Gene ID 6093, 19877, 698223, 81762, 101092552, 480181, 785911, 100034056
    Gene Symbol and Synonyms 1110055K06Rik,P160ROCK,ROCK-I,ROCK1
    Uniprot Accession Q13464
    Uniprot Entry Name ROCK1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000067900
    Target Classification Kinase, Tumor-associated antigen (TAA)

    This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]

    About GMVC


    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.