Human ROCK1/P160ROCK/ ROCK-I ORF/cDNA clone-Lentivirus particle (NM_005406.2)

Pre-made Human ROCK1/P160ROCK/ ROCK-I Lentiviral expression plasmid for ROCK1 lentivirus packaging, ROCK1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.

Target products collectionGo to ROCK1/P160ROCK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLV000212 Human ROCK1 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLV000212
Gene Name ROCK1
Accession Number NM_005406.2
Gene ID 6093
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 4065 bp
Gene Alias P160ROCK, ROCK-I
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T51282-Ab Anti-ROCK1 monoclonal antibody
    Target Antigen GM-Tg-g-T51282-Ag ROCK1 protein
    ORF Viral Vector pGMLV000212 Human ROCK1 Lentivirus plasmid
    ORF Viral Vector vGMLV000212 Human ROCK1 Lentivirus particle


    Target information

    Target ID GM-T51282
    Target Name ROCK1
    Gene ID 6093, 19877, 698223, 81762, 101092552, 480181, 785911, 100034056
    Gene Symbol and Synonyms 1110055K06Rik,P160ROCK,ROCK-I,ROCK1
    Uniprot Accession Q13464
    Uniprot Entry Name ROCK1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000067900
    Target Classification Kinase, Tumor-associated antigen (TAA)

    This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.