Human CD40LG/CD154/ CD40L ORF/cDNA clone-Lentivirus plasmid (NM_000074)

Pre-made Human CD40LG/CD154/ CD40L Lentiviral expression plasmid for CD40LG lentivirus packaging, CD40LG lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collectionGo to CD40LG/CD154 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000459 Human CD40LG Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMLV000459
Gene Name CD40LG
Accession Number NM_000074
Gene ID 959
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 786 bp
Gene Alias CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-132 Pre-Made Dapirolizumab biosimilar, Fab, Anti-CD40LG Antibody: Anti-IGM/IMD3/TRAP/gp39/CD154/CD40L/HIGM1/T-BAM/TNFSF5/hCD40L therapeutic antibody
    Biosimilar GMP-Bios-ab-501 Pre-Made Ruplizumab biosimilar, Whole mAb, Anti-CD40LG Antibody: Anti-IGM/IMD3/TRAP/gp39/CD154/CD40L/HIGM1/T-BAM/TNFSF5/hCD40L therapeutic antibody
    Biosimilar GMP-Bios-INN-1026 Pre-Made Toralizumab Biosimilar, Whole Mab, Anti-Cd40Lg Antibody: Anti-CD154/CD40L/HIGM1/IGM/IMD3/T-BAM/TNFSF5/TRAP/gp39/hCD40L therapeutic antibody
    Biosimilar GMP-Bios-INN-798 Pre-Made Dazodalibep Biosimilar, Fusion Protein targeting CD40LG fused with ALB (albumin, human serum albumin, HSA): Recombinant therapeutic protein targeting CD154/CD40L/HIGM1/IGM/IMD3/T-BAM/TNFSF5/TRAP/gp39/hCD40L
    Biosimilar GMP-Bios-ab-307 Pre-Made Letolizumab biosimilar, Single Domain Variable Fragment;H, Anti-CD40LG Antibody: Anti-IGM/IMD3/TRAP/gp39/CD154/CD40L/HIGM1/T-BAM/TNFSF5/hCD40L therapeutic antibody
    Target Antibody GM-Tg-g-T14755-Ab Anti-CD40L/ CD40LG/ CD154 monoclonal antibody
    Target Antigen GM-Tg-g-T14755-Ag CD40LG VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T14755 CD40 ligand (CD154) protein & antibody
    ORF Viral Vector pGMLV000459 Human CD40LG Lentivirus plasmid
    ORF Viral Vector pGMAP000295 Human CD40LG Adenovirus plasmid
    ORF Viral Vector vGMLV000459 Human CD40LG Lentivirus particle
    ORF Viral Vector vGMAP000295 Human CD40LG Adenovirus particle


    Target information

    Target ID GM-T14755
    Target Name CD40LG
    Gene ID 959, 21947, 574160, 84349, 493850, 403468, 100054624
    Gene Symbol and Synonyms CD154,CD40-L,CD40L,CD40LG,gp39,hCD40L,HIGM1,IGM,IMD3,Ly-62,Ly62,T-BAM,TNFSF5,Tnlg8b,TRAP
    Uniprot Accession P29965
    Uniprot Entry Name CD40L_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
    Disease Not Available
    Gene Ensembl ENSG00000102245
    Target Classification Checkpoint-Immuno Oncology

    The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]



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