Human SIRT3/SIR2L3 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_012239.5)

Cat. No.: pGMPC000237
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SIRT3/SIR2L3 Non-Viral expression plasmid (overexpression vector) for mouse SIRT3 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000237
Gene Name SIRT3
Accession Number NM_012239.5
Gene ID 23410
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1200 bp
Gene Alias SIR2L3
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag HA (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCGTTCTGGGGTTGGCGCGCCGCGGCAGCCCTCCGGCTGTGGGGCCGGGTAGTTGAACGGGTCGAGGCCGGGGGAGGCGTGGGGCCGTTTCAGGCCTGCGGCTGTCGGCTGGTGCTTGGCGGCAGGGACGATGTGAGTGCGGGGCTGAGAGGCAGCCATGGGGCCCGCGGTGAGCCCTTGGACCCGGCGCGCCCCTTGCAGAGGCCTCCCAGACCCGAGGTGCCCAGGGCATTCCGGAGGCAGCCGAGGGCAGCAGCTCCCAGTTTCTTCTTTTCGAGTATTAAAGGTGGAAGAAGGTCCATATCTTTTTCTGTGGGTGCTTCAAGTGTTGTTGGAAGTGGAGGCAGCAGTGACAAGGGGAAGCTTTCCCTGCAGGATGTAGCTGAGCTGATTCGGGCCAGAGCCTGCCAGAGGGTGGTGGTCATGGTGGGGGCCGGCATCAGCACACCCAGTGGCATTCCAGACTTCAGATCGCCGGGGAGTGGCCTGTACAGCAACCTCCAGCAGTACGATCTCCCGTACCCCGAGGCCATTTTTGAACTCCCATTCTTCTTTCACAACCCCAAGCCCTTTTTCACTTTGGCCAAGGAGCTGTACCCTGGAAACTACAAGCCCAACGTCACTCACTACTTTCTCCGGCTGCTTCATGACAAGGGGCTGCTTCTGCGGCTCTACACGCAGAACATCGATGGGCTTGAGAGAGTGTCGGGCATCCCTGCCTCAAAGCTGGTTGAAGCTCATGGAACCTTTGCCTCTGCCACCTGCACAGTCTGCCAAAGACCCTTCCCAGGGGAGGACATTCGGGCTGACGTGATGGCAGACAGGGTTCCCCGCTGCCCGGTCTGCACCGGCGTTGTGAAGCCCGACATTGTGTTCTTTGGGGAGCCGCTGCCCCAGAGGTTCTTGCTGCATGTGGTTGATTTCCCCATGGCAGATCTGCTGCTCATCCTTGGGACCTCCCTGGAGGTGGAGCCTTTTGCCAGCTTGACCGAGGCCGTGCGGAGCTCAGTTCCCCGACTGCTCATCAACCGGGACTTGGTGGGGCCCTTGGCTTGGCATCCTCGCAGCAGGGACGTGGCCCAGCTGGGGGACGTGGTTCACGGCGTGGAAAGCCTAGTGGAGCTTCTGGGCTGGACAGAAGAGATGCGGGACCTTGTGCAGCGGGAAACTGGGAAGCTTGATGGACCAGACAAATAG
ORF Protein Sequence MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T91959-Ab Anti-SIRT3 monoclonal antibody
    Target Antigen GM-Tg-g-T91959-Ag SIRT3 protein
    ORF Viral Vector pGMLP002811 Human SIRT3 Lentivirus plasmid
    ORF Viral Vector pGMLV000991 Human SIRT3 Lentivirus plasmid
    ORF Viral Vector pGMLV001438 Human SIRT3 Lentivirus plasmid
    ORF Viral Vector pGMAD000249 Human SIRT3 Adenovirus plasmid
    ORF Viral Vector pGMAD000464 Human SIRT3 Adenovirus plasmid
    ORF Viral Vector pGMPC000237 Human SIRT3 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000393 Human SIRT3 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000866 Human SIRT3 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP002811 Human SIRT3 Lentivirus particle
    ORF Viral Vector vGMLV000991 Human SIRT3 Lentivirus particle
    ORF Viral Vector vGMLV001438 Human SIRT3 Lentivirus particle
    ORF Viral Vector vGMAD000249 Human SIRT3 Adenovirus particle
    ORF Viral Vector vGMAD000464 Human SIRT3 Adenovirus particle


    Target information

    Target ID GM-T91959
    Target Name SIRT3
    Gene ID 23410, 64384, 720737, 293615, 101087609, 475933, 614027, 100054908
    Gene Symbol and Synonyms 2310003L23Rik,SIR2L3,SIRT3
    Uniprot Accession Q9NTG7
    Uniprot Entry Name SIR3_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000142082
    Target Classification Not Available

    SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]



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