Human CLDN1/CLD1/ILVASC ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_021101.5)

Cat. No.: pGMPC000975
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CLDN1/CLD1/ILVASC Non-Viral expression plasmid (overexpression vector) for mouse CLDN1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000975
Gene Name CLDN1
Accession Number NM_021101.5
Gene ID 9076
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 636 bp
Gene Alias CLD1,ILVASC,SEMP1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCCAACGCGGGGCTGCAGCTGTTGGGCTTCATTCTCGCCTTCCTGGGATGGATCGGCGCCATCGTCAGCACTGCCCTGCCCCAGTGGAGGATTTACTCCTATGCCGGCGACAACATCGTGACCGCCCAGGCCATGTACGAGGGGCTGTGGATGTCCTGCGTGTCGCAGAGCACCGGGCAGATCCAGTGCAAAGTCTTTGACTCCTTGCTGAATCTGAGCAGCACATTGCAAGCAACCCGTGCCTTGATGGTGGTTGGCATCCTCCTGGGAGTGATAGCAATCTTTGTGGCCACCGTTGGCATGAAGTGTATGAAGTGCTTGGAAGACGATGAGGTGCAGAAGATGAGGATGGCTGTCATTGGGGGTGCGATATTTCTTCTTGCAGGTCTGGCTATTTTAGTTGCCACAGCATGGTATGGCAATAGAATCGTTCAAGAATTCTATGACCCTATGACCCCAGTCAATGCCAGGTACGAATTTGGTCAGGCTCTCTTCACTGGCTGGGCTGCTGCTTCTCTCTGCCTTCTGGGAGGTGCCCTACTTTGCTGTTCCTGTCCCCGAAAAACAACCTCTTACCCAACACCAAGGCCCTATCCAAAACCTGCACCTTCCAGCGGGAAAGACTACGTGTGA
ORF Protein Sequence MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0271-Ab Anti-CLD1/ CLDN1/ ILVASC monoclonal antibody
    Target Antigen GM-Tg-g-MP0271-Ag CLDN1 VLP (virus-like particle)
    ORF Viral Vector pGMLV000077 Human CLDN1 Lentivirus plasmid
    ORF Viral Vector pGMLV001928 Human CLDN1 Lentivirus plasmid
    ORF Viral Vector pGMPC000975 Human CLDN1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000077 Human CLDN1 Lentivirus particle
    ORF Viral Vector vGMLV001928 Human CLDN1 Lentivirus particle


    Target information

    Target ID GM-MP0271
    Target Name CLDN1
    Gene ID 9076, 12737, 704330, 65129, 101094619, 608207, 414922, 100059811
    Gene Symbol and Synonyms claudin-1,CLD1,CLDN1,ILVASC,SEMP1
    Uniprot Accession O95832
    Uniprot Entry Name CLD1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000163347
    Target Classification Tumor-associated antigen (TAA)

    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]



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