Human FLT1/FLT/ FLT-1 ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_002019.4)

Pre-made Human FLT1/FLT/ FLT-1 Adeno-associated virus particle for FLT1 in-vivo study, mechanism of action (MOA) research and FLT1-associated gene therapy development.

At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.

Target products collectionGo to FLT-1/FLT1/FLT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name AAV serotype AAV Grade AAV quantity
vGMAAV000141 Human FLT1 Adeno-associate virus(AAV) particle AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF Pilot Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
Research Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAAV000141
Gene Name FLT1
Accession Number NM_002019.4
Gene ID 2321
Species Human
Product Type Adeno-associate virus(AAV) particle (overexpression)
Insert Length 4017 bp
Gene Alias FLT, FLT-1, VEGFR-1, VEGFR1
Fluorescent Reporter EGFP
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-259 Pre-Made Icrucumab biosimilar, Whole mAb, Anti-FLT1/FLT-1 Antibody: Anti-VEGFR-1/VEGFR1 therapeutic antibody
    Target Antibody GM-Tg-g-T63966-Ab Anti-VGFR1/ FLT-1/ FLT1 monoclonal antibody
    Target Antigen GM-Tg-g-T63966-Ag FLT-1/FLT1 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T63966 fms-related tyrosine kinase 1 (FLT1) protein & antibody
    ORF Viral Vector pGMLV000309 Human FLT1 Lentivirus plasmid
    ORF Viral Vector pGMLV000970 Human FLT1 Lentivirus plasmid
    ORF Viral Vector pGMAD000439 Human FLT1 Adenovirus plasmid
    ORF Viral Vector pGMAAV000141 Human FLT1 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMPC000032 Human FLT1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000039 Human FLT1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000309 Human FLT1 Lentivirus particle
    ORF Viral Vector vGMLV000970 Human FLT1 Lentivirus particle
    ORF Viral Vector vGMAD000439 Human FLT1 Adenovirus particle
    ORF Viral Vector vGMAAV000141 Human FLT1 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-T63966
    Target Name FLT-1
    Gene ID 2321, 14254, 574133, 54251, 101088292, 403727, 503620, 100033957
    Gene Symbol and Synonyms FLT,FLT-1,FLT1,sFlt1,VEGFR-1,VEGFR1
    Uniprot Accession P17948
    Uniprot Entry Name VGFR1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
    Disease Breast Cancer
    Gene Ensembl ENSG00000102755
    Target Classification Checkpoint-Immuno Oncology, Kinase

    This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.