Bovine immunodeficiency virus antibody and antigen (recombinant protein)

 Download 

Diagnostic anti-Bovine immunodeficiency virus antibodies pairs and antigen for animal health (animal Bovines/Cattle infectious disease immune dysfunction) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Go to Ruminants disease testing products collection >>

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P091-Ag01	Recombinant Bovine immunodeficiency virus protein	$3090.00
GMP-VT-P091-Ab01	Anti-Bovine immunodeficiency virus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P091-Ab02	Anti-Bovine immunodeficiency virus mouse monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P091-Ag01
Product Name	Recombinant Bovine immunodeficiency virus protein
Pathogen	Bovine immunodeficiency virus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine immunodeficiency virus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Bovine immunodeficiency virus level test of animal Bovines/Cattle infectious disease with immune dysfunction.
Tag	His
Product description	Recombinant Bovine immunodeficiency virus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P091-Ab01,GMP-VT-P091-Ab02
Pathogen	Bovine immunodeficiency virus
Product Name	Anti-Bovine immunodeficiency virus mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine immunodeficiency virus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine immunodeficiency virus antibodies in Bovine immunodeficiency virus level test of animal Bovines/Cattle infectious disease with immune dysfunction.
Product description	Anti-Bovine immunodeficiency virus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine immunodeficiency virus antibodies./td>
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Pathogen

1. Pathogen Common Name: Brachyspira hyodysenteriae

Brachyspira hyodysenteriae is a pathogenic bacterium known to cause swine dysentery, a highly contagious and economically significant disease in pigs. This pathogen primarily affects the large intestine of swine and is responsible for a range of clinical symptoms, including bloody diarrhea, weight loss, and decreased feed efficiency.

2. Classification:

Brachyspira hyodysenteriae is a prokaryotic bacterium. It belongs to the family Brachyspiraceae and the order Spirochaetales. This bacterium is characterized by its spiral or helical shape and is classified as a spirochete.

3. Structure (Main Gene and Protein):

Brachyspira hyodysenteriae has a complex structure, as is typical of spirochetes. The outer membrane of this bacterium contains various proteins, including adhesins, which are involved in its pathogenicity. One of the important proteins is the Hemolysin, which plays a role in damaging host cells and contributing to the clinical symptoms of swine dysentery.

4. Hosts Infected: The primary host infected by Brachyspira hyodysenteriae is swine, specifically domestic pigs.

5. Diseases Caused: This pathogen is responsible for causing swine dysentery, a disease characterized by mucoid and often bloody diarrhea in infected pigs. Swine dysentery can lead to substantial economic losses in the swine industry due to decreased growth rates and increased mortality.

6. Diagnostic Methods:

There are several diagnostic methods for detecting Brachyspira hyodysenteriae, including culture-based, serological, and molecular techniques. Nucleic acid-based methods have become increasingly important for their speed and accuracy. These methods can target specific genes and proteins. Some of the key genes and proteins targeted in diagnostic methods include:

7. 16S rRNA Gene: This gene is often used for PCR-based detection of Brachyspira hyodysenteriae.

8. NADH oxidase (nox) Gene: The nox gene is specific to Brachyspira hyodysenteriae and can be targeted for molecular diagnostics.

9. Hemolysin Protein: Some diagnostic methods target the Hemolysin protein, which is specific to Brachyspira hyodysenteriae and plays a role in its pathogenicity.

These diagnostic methods help in the early and accurate detection of the pathogen in swine populations, allowing for timely intervention and control of the disease.

For a biopharmaceutical company, understanding and combating pathogens like Brachyspira hyodysenteriae is essential for the development of treatments and vaccines to protect swine populations and reduce economic losses in the swine industry.

About GDU