Campylobacter antibody and antigen (recombinant protein)

Diagnostic anti-Campylobacter antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease Campylobacteriosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P202-Ag01 Recombinant Campylobacter protein $3090.00
GMP-VT-P202-Ab01 Anti-Campylobacter mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P202-Ab02 Anti-Campylobacter mouse monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P202-Ag01
Product Name Recombinant Campylobacter protein
Pathogen Campylobacter
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Campylobacter antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Campylobacter level test of animal Avian/Bird/Poultry infectious disease with Campylobacteriosis.
Tag His
Product description Recombinant Campylobacter proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P202-Ab01,GMP-VT-P202-Ab02
Pathogen Campylobacter
Product Name Anti-Campylobacter mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Campylobacter antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Campylobacter antibodies in Campylobacter level test of animal Avian/Bird/Poultry infectious disease with Campylobacteriosis.
Product description Anti-Campylobacter mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Campylobacter antibodies./td>
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Pathogen


    Campylobacter is a genus of microaerophilic, spiral-shaped, Gram-negative bacteria that are commonly found in the intestines of animals, including poultry, cattle, sheep, pigs, and pets. Two species in particular, Campylobacter jejuni and Campylobacter coli, are responsible for the majority of human infections caused by this pathogen.

    One of the defining features of Campylobacter is its ability to move through fluids and across surfaces via its flagella, which are whip-like structures that provide the bacteria with motility. The primary proteins involved in flagellar movement are encoded by the flaA and flaB genes, which respectively produce major flagellin proteins that form the flagellar filaments.

    Another protein produced by Campylobacter is the cadF protein, which mediates adhesion to host cells and facilitates invasion. The luxS gene encodes an enzyme that is involved in quorum-sensing, which allows bacteria to communicate with one another to coordinate group behaviors such as biofilm formation. Finally, the cdtABC genes encode for the cytolethal distending toxin, which can cause cell cycle arrest, ultimately leading to cell death.

    When humans become infected with Campylobacter, it is often through consumption of contaminated food or water, or by coming into contact with infected animals or their feces. Once inside the body, these bacteria can cause a range of gastrointestinal diseases, including diarrhea, fever, abdominal pain, and vomiting. Symptoms usually appear within 2-5 days after infection and typically last for about a week.

    To diagnose Campylobacter infections, several methods are available. Culture-based methods involve growing the bacteria on selective media, which can be time-consuming and may take up to two weeks to obtain results. Alternatively, PCR assays can target specific Campylobacter genes such as the 16S rRNA and cadF genes, allowing for more rapid detection of the pathogen.

    ELISA tests are another diagnostic option that detect antibodies against Campylobacter-specific antigens such as the flaA protein. These tests are often used in outbreak scenarios to determine the extent of infection in a population.

    Fortunately, Campylobacter infections can be prevented through proper food handling and preparation, as well as good hygiene practices such as frequent hand washing. Additionally, efforts to reduce Campylobacter in agriculture and food production have been ongoing, with measures such as vaccination of animals and use of probiotics being explored as potential solutions.

    In summary, Campylobacter is a genus of microaerophilic, spiral-shaped, Gram-negative bacteria commonly found in animals that can cause serious gastrointestinal diseases in humans. While multiple diagnostic methods are available, prevention through good hygiene and appropriate food handling remains the best way to avoid infection.



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