Duck Circovirus antibody and antigen (recombinant protein)

Diagnostic anti-Duck Circovirus antibodies pairs and antigen for animal health (animal Duck infectious disease immunosuppression) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Avian/Bird/Poultry disease testing products collection >>


Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P203-Ag01 Recombinant Duck Circovirus protein $3090.00
GMP-VT-P203-Ab01 Anti-Duck Circovirus mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P203-Ab02 Anti-Duck Circovirus mouse monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P203-Ag01
Product Name Recombinant Duck Circovirus protein
Pathogen Duck Circovirus
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Duck Circovirus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Duck Circovirus level test of animal Duck infectious disease with immunosuppression.
Tag His
Product description Recombinant Duck Circovirus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P203-Ab01,GMP-VT-P203-Ab02
Pathogen Duck Circovirus
Product Name Anti-Duck Circovirus mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Duck Circovirus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Duck Circovirus antibodies in Duck Circovirus level test of animal Duck infectious disease with immunosuppression.
Product description Anti-Duck Circovirus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Duck Circovirus antibodies./td>
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


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    Pathogen


    Duck Circovirus (DuCV): A Comprehensive Overview

    Duck Circovirus, scientifically known as Duck Circovirus (DuCV), is a notable pathogen with a significant impact on avian populations, particularly ducks. This article provides an in-depth exploration of this virus, encompassing its nomenclature, classification, genomic structure, associated diseases, and diagnostic methods.

    Names of the Pathogen

    Duck Circovirus, as it is commonly referred to, possesses a comprehensive nomenclature denoting its different types. It is often identified by the following names:

    Duck Circovirus (DuCV): The generic term for this pathogen.

    Duck Circovirus Type 1 (DuCV-1): A specific strain or variant of DuCV.

    Duck Circovirus Type 2 (DuCV-2): Another variant, distinct from DuCV-1.

    Pathogen Classification

    Duck Circovirus is a member of the viral kingdom, characterized by its classification as a prokaryotic virus. It belongs to the Circoviridae family, which encompasses a unique group of viruses with circular, single-stranded DNA genomes. The distinct genomic and structural features place Duck Circovirus among a subset of viruses known for their circular DNA configuration.

    Pathogen Structure

    Understanding the structure of Duck Circovirus is essential to grasp its mode of action and the implications it has on infected hosts. The virus primarily comprises two critical components:

    Genomic Structure: The primary genomic entity of Duck Circovirus is a circular single-stranded DNA molecule. This circular configuration, unique to members of the Circoviridae family, presents specific challenges and opportunities for replication and maintenance. The circular genome contains essential genetic information vital for the viral life cycle.

    Replication-Associated Protein (Rep): Rep is a pivotal element of Duck Circovirus. This protein plays a central role in the replication of the viral genome. It acts as an indispensable factor in ensuring the virus's ability to reproduce and propagate within its host. The Rep protein is a critical target for both diagnostics and understanding the molecular biology of Duck Circovirus.

    Capsid Protein: The viral capsid is another essential structural component. Composed of capsid proteins, it encapsulates the viral genome, providing protection and stability to the virus. The capsid structure is vital for the integrity of Duck Circovirus and its infectivity.

    Hosts Infected and Diseases

    Duck Circovirus primarily targets avian species, with ducks being the most commonly affected hosts. The consequences of infection are substantial, leading to a range of diseases. These diseases include:

    Duck Beak and Feather Disease (DBFD): This condition is a hallmark of Duck Circovirus infection. It manifests as a series of distinctive symptoms, including feather abnormalities, beak deformities, and immunosuppression. Ducks afflicted by DBFD experience severe feather loss and beak malformations, impacting their overall health and rendering them vulnerable to secondary infections due to immunosuppression.

    Runting-Stunting Syndrome (RSS): Another notable disease associated with Duck Circovirus infection is RSS. Ducks suffering from RSS exhibit growth retardation, resulting in reduced weight gain and overall developmental issues. This syndrome has implications not only for individual ducks but also for the productivity and economics of the poultry industry.

    Understanding these diseases and their association with Duck Circovirus is vital for the management of avian populations, especially in the context of commercial duck farming.

    Diagnostic Methods

    Accurate and timely diagnosis of Duck Circovirus is crucial for disease management and epidemiological surveillance. Several diagnostic methods are available, many of which are nucleic acid-based techniques. These methods include:

    Polymerase Chain Reaction (PCR): PCR is a powerful and highly sensitive method for detecting Duck Circovirus DNA. Specific primer sets can be designed to target regions of the viral genome, including the Rep gene. The amplification of these specific sequences allows for precise and efficient detection of the virus.

    Loop-Mediated Isothermal Amplification (LAMP): LAMP is an isothermal nucleic acid amplification technique that offers rapid and specific detection of Duck Circovirus. Like PCR, LAMP can be designed to target distinct genomic regions, ensuring accurate identification.

    Southern Blotting: Southern blotting is a molecular technique used to confirm the presence of Duck Circovirus DNA in a sample. This method involves the use of specific probes designed to target viral DNA sequences, allowing for the visualization and confirmation of viral DNA.

    In Situ Hybridization (ISH): ISH is a valuable technique for detecting Duck Circovirus DNA in infected tissues. This method provides a means of visualizing the viral DNA within the host, which is particularly useful for confirming the presence of the virus.

    Enzyme-Linked Immunosorbent Assay (ELISA): ELISA-based tests can target specific viral proteins, such as the capsid protein. By detecting the presence of these proteins, ELISA tests provide an alternative approach to identifying Duck Circovirus. While it doesn't directly target the viral genome, it aids in virus detection through the detection of viral proteins.

    These diagnostic methods are instrumental in the identification and surveillance of Duck Circovirus in avian populations. They enable early detection, which is vital for implementing appropriate control measures and mitigating the impact of the associated diseases.

    In conclusion, Duck Circovirus, a member of the Circoviridae family, is a pathogen of significant concern for avian health, particularly among duck populations. Understanding its structure, associated diseases, and diagnostic methods is paramount for effective disease management and maintaining the health of domestic and wild waterfowl. Accurate and timely diagnosis, through nucleic acid-based techniques and protein detection, is essential for addressing the challenges posed by Duck Circovirus and ensuring the well-being of these avian species.



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