TMBIM1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of TMBIM1. The page also collects GeneMedi's different modalities and formats products for TMBIM1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the TMBIM1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Enables death receptor binding activity. Involved in negative regulation of Fas signaling pathway; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of protein localization to plasma membrane. Located in Golgi apparatus; endosome membrane; and lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022]
Target ID | GM-MP1805 |
Target Name | TMBIM1 |
Gene ID | 64114,69660,316516,698325,102153649,101086997,404134,100055634 |
Gene Symbol and Synonyms | 2310061B02Rik,LFG3,mKIAA4161,MST100,MSTP100,PP1201,RECS1,Tmbib1,TMBIM1 |
Uniprot Accession | Q969X1 |
Uniprot Entry Name | LFG3_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000135926 |
Target Classification | N/A |
Pre-made anti-TMBIM1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-TMBIM1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TMBIM1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-TMBIM1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species LFG3/ TMBIM1/ MST100 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMBIM1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
TMBIM1 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made TMBIM1 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLP003188 | human TMBIM1 Lentivirus plasmid | NM_022152 | Human | Lentivirus plasmid | Detail |
vGMAD000119 | human TMBIM1 Adenovirus particle | NM_001321432.1 | Human | Adenovirus particle | Detail |
pGMAD000119 | human TMBIM1 Adenovirus plasmid | NM_001321432.1 | Human | Adenovirus plasmid | Detail |
vGMAD000120 | human TMBIM1 Adenovirus particle | NM_001321432.1 | Human | Adenovirus particle | Detail |
pGMAD000120 | human TMBIM1 Adenovirus plasmid | NM_001321432.1 | Human | Adenovirus plasmid | Detail |
vGMLP003188 | human TMBIM1 Lentivirus particle | NM_022152 | Human | Lentivirus particle | Detail |
pGMAD000334 | mouse Tmbim1 Adenovirus plasmid | NM_027154.5 | Mouse | Adenovirus plasmid | Detail |
pGMAAV000293 | Norway rat Tmbim1 AAV plasmid | NM_001007713 | Norway Rat | AAV plasmid | Detail |
vGMAD000334 | mouse Tmbim1 Adenovirus particle | NM_027154.5 | Mouse | Adenovirus particle | Detail |
vGMAAV000293 | Norway rat Tmbim1 AAV particle | NM_001007713 | Norway Rat | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.